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Recombinant Kinase Proteins

Our collection of Recombinant Kinase Proteins offers high-quality, functionally active enzymes critical for dissecting cellular signaling pathways and developing novel inhibitors. Produced using insect, mammalian, or bacterial expression systems, our kinases provide precise enzymatic activity and consistent reproducibility to meet the rigorous demands of advanced scientific research and pharmaceutical development.

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Target
Description
Price
A-Raf, active Human Recombinant Kinase Protein
Protein Serine/Threonine Kinases
N-terminal GST-tagged recombinant, human A-Raf amino acids 273-end containing the mutations Y301D and Y302D.
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€ 389,00 EUR
10 µg of active Abl (H396P). N-terminal 6His-tagged recombinant, human Abl, amino acids 27-end containing the H396P mutation.
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€ 389,00 EUR
AAK1, active Human Recombinant Kinase Protein
Protein Serine/Threonine Kinases
10 µg of active AAK1. N-terminal 6His-tagged, recombinant fragment of human AAK1.
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€ 389,00 EUR
10 µg of active Abl (M351T). N-terminal 6His-tagged recombinant, human Abl, amino acids 27-end containing the M351T mutation.
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€ 389,00 EUR
10 µg of active Abl (Q252H). N-terminal 6His-tagged recombinant, human Abl, amino acids 27-end containing the Q252H mutation.
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€ 389,00 EUR
N-terminal 6His-tagged recombinant, human Abl, amino acids 27-end containing the T315I mutation. Contains the gatekeeper mutation T315I in the ATP-binding domain. This mutation decreases the sensitivity to Gleevec® by more than 200-fold as compared to the wild type sequence.
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€ 389,00 EUR
N-terminal 6His-tagged recombinant, murine Abl amino acids 27-1123.
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€ 389,00 EUR
10 µg of active Abl (Y253F). N-terminal 6His-tagged recombinant, human Abl, amino acids 27-end containing the Y253F mutation.
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€ 389,00 EUR
N-terminal 6His-tagged recombinant, human Abl, amino acids 27-end.
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€ 389,00 EUR
N-terminal GST-tagged recombinant, human ACK1, amino acids 1-389.
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€ 389,00 EUR
ACTR2, active Human Recombinant Kinase Protein
Protein Serine/Threonine Kinases
10 µg of active ACTR2. N-terminal GST-tagged, recombinant, human ACTR2 amino acids 162-end.
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€ 389,00 EUR
ActRIIB, active Human Recombinant Kinase Protein
Protein Serine/Threonine Kinases
10 µg of active ActRIIB. N-Terminal GST-tagged, recombinant, human ActRIIB amino acids 185-488.
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€ 389,00 EUR
N-terminal 6His-tagged recombinant, human Akt1, amino acids 118-end containing the mutation S473D.
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€ 389,00 EUR
N-terminal 6His-tagged recombinant, human full length Akt1.
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€ 389,00 EUR
N-terminal 6His-tagged recombinant, human full length Akt1.
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€ 389,00 EUR
N-terminal 6His-tagged recombinant, human PKBβ, amino acids 120-481, S474D; activated by PDK1.
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€ 389,00 EUR
N-terminal 6His-tagged recombinant, human Akt3/PKBγ amino acids 117-end, containing a S472D mutation.
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€ 389,00 EUR
Alk, active Human Recombinant Kinase Protein
Protein Serine/Threonine Kinases
N-terminal 6His-tagged recombinant, human ALK, amino acids 1058-end.
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€ 389,00 EUR
ALK1, active Human Recombinant Kinase Protein
Protein Serine/Threonine Kinases
N-terminal 6His-tagged recombinant, human ALK1 amino acids 142-end.
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€ 389,00 EUR
ALK2, active Human Recombinant Kinase Protein
Protein Serine/Threonine Kinases
10 µg of active ALK2. N-terminal 6His-tagged recombinant, human ALK2 amino acids 147-end.
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€ 389,00 EUR

Recombinant Kinase Proteins Key Features and Benefits

Extensive Kinase Portfolio - Explore a diverse catalog that includes active, inactive, and mutant kinases spanning various families tyrosine, serine/threonine, lipid kinases, and more designed for both fundamental research and drug discovery applications.

Optimized Expression Systems - Our proteins are produced using carefully selected expression systems to ensure correct folding and post-translational modifications, which are critical for accurate enzymatic function and assay performance.

High-Quality Assurance - Careful performance optimization and rigorous quality control procedures are implemented to guarantee the highest specific activity, and consistency from one batch to another, ensuring reliable and reproducible results.

Variety of Sizes - The product line offers flexibility with multiple packaging sizes and bulk options. Whether you need enzymes for a one-time experiment or a large-scale high-throughput screening (HTS) campaign, there are sizing options to meet your specific requirements.

Versatile Research Applications

Drug Discovery - Screen and optimize kinase inhibitors with high-precision binding and inhibition studies.

Signaling Pathway Analysis - Decode kinase regulation and mutation effects in complex cellular networks.

High-Throughput Screening - Enable large-scale inhibitor or activator screening with custom assay designs.

Structure-Function Studies: - Investigate kinase-ligand interactions and conformational dynamics with confidence.

Customize Your Assays with ADP Hunter Plus

Maximize control by pairing our recombinant kinases with ADP Hunter Plus detection reagents. This powerful combination lets you build tailored kinase activity assays, fine-tuning substrate concentrations, ATP levels, reaction timing, and kinetic parameters. Ideal for optimizing high-throughput screening (HTS) in multi-well formats or diving deep into mechanistic hypotheses, this modular approach delivers the precision and sensitivity your research demands.

All-in-One Alternative: HitHunter Kinase Enzyme Activity Assay Kits

Prefer a ready-to-use solution? Our Complete HitHunter Kinase Enzyme Activity Assay Kits provide everything you need in one validated package—recombinant kinases, matched substrates, detection reagents, and buffers. Engineered for high specificity and sensitivity, these kits support low- to high-throughput screening (HTS), with a robust ADP detection platform tolerant to elevated ATP levels (up to 1 mM).

Customized Solutions: Tailored Kinase Development

Need a purified recombinant kinase that is currently unavailable or required in a customized format? Our Custom Development Services craft recombinant kinases to your exact specifications. From rare, understudied kinases or specific recombinant configurations to custom mutations, our experts partner with you to deliver tailored enzymes that push your research and drug discovery forward.

Advance Your Research with Recombinant Kinases

Take your kinase studies to the next level—order our Recombinant Kinase Proteins today and unlock unparalleled research potential. For tailored solutions, fill out our Design Your Project Form or Contact Us to connect with our kinase specialists and accelerate your next breakthrough.

Secure and boost
your discovery programs

Starting from native material or recombinant systems, we succeed with all types of proteins: Kinases, Phosphatases, Ubiquitins, Epigenetic Proteins, GPCRs, Ion Channels, Transporters, Receptors and Viral Proteins.