Eurofins CALIXAR offers full-length, native, and functional GPCRs. We overexpress, solubilize, stabilize and purify our GPCRs with our patented technologies, so we can offer you the highest quality proteins.
We use standard quality tests to confirm:
- Purity (SDS-PAGE, UV Spectrum…)
- Stability (Thermal Shift Assay, Cryo-Stability Assay…)
- Homogeneity (SEC, DLS…)
- Functionality (Ligand Binding Assay, Ion Flux Assay, Enzymatic Activity…)
Transporters are part of membrane protein, involved in nutrient capture, antibiotic efflux, protein secretion, toxin production, photosynthesis, oxidative phosphorylation, photosynthesis, environmental sensing, and other vital functions in all organisms.
Therapeutics molecules are mainly linked to Transporters because drugs are vehicles from different biologic membranes. Transporters ensure the absorption and distribution roles of drugs in various kinds of tissue (placenta, kidney, central nervous system).
All actors involved in life science projects can benefit from purified membrane proteins: pharmaceutical companies, biotechnology companies, and academic research centers.
Our Transporters are most suited for these types of life science projects:
- Drug Discovery
- Antibody Discovery
- Vaccine Discovery
Eurofins CALIXAR’s Transporters are powerful therapeutic targets for projects of multi-drug resistance studies involving bacterial resistance to antibiotics.
With Eurofins CALIXAR’s Transporters, our clients can develop and validate new molecules and therapeutics antibodies. These targets are produced full-length and by maintaining their integral functions and conformity which allow them to obtain the best results in terms of development and validation of drugs.
Thanks to their high purity and stability, CALIXAR’s Transporters can avoid interferences in discovery programs due to less pure and functional membrane proteins.
Secure and boost
your discovery programs
Starting from native material or recombinant systems, we succeed with all types of proteins: Kinases, Phosphatases, Ubiquitins, Epigenetic Proteins, GPCRs, Ion Channels, Transporters, Receptors and Viral Proteins.