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Transporters

Eurofins CALIXAR’s transporters are essential targets for drug discovery, structural biology, and fundamental research. Our commitment to advancing transporter research drives us to provide high-quality transporter products that empower scientists and researchers worldwide. Transporter proteins are integral membrane proteins responsible for the selective movement of molecules across cell membranes. They play a critical role in nutrient uptake, waste removal, and the regulation of ions and metabolites within cells. Understanding transporter function is crucial for elucidating cellular processes and developing targeted therapies. Here are some of our transporter targets that are currently available for purchase.

Target
Description
Price
Recombinant Multidrug efflux pump subunit AcrB, full-length, wildtype sequence, C-terminus 6xHis-tag
Select an option
€ 220,00 EUR
Recombinant Multidrug resistance ABC transporter ATP-binding/permease protein BmrA, full-length, wildtype sequence, N-terminus 6xHis-tag
Select an option
€ 220,00 EUR

Product highlights

Eurofins CALIXAR offers full-length, native, and functional GPCRs. We overexpress, solubilize, stabilize and purify our GPCRs with our patented technologies, so we can offer you the highest quality proteins.

We use standard quality tests to confirm:

  • Purity (SDS-PAGE, UV Spectrum…)
  • Stability (Thermal Shift Assay, Cryo-Stability Assay…)
  • Homogeneity (SEC, DLS…)
  • Functionality (Ligand Binding Assay, Ion Flux Assay, Enzymatic Activity…)

Transporter’s functions

Transporters are part of membrane protein, involved in nutrient capture, antibiotic efflux, protein secretion, toxin production, photosynthesis, oxidative phosphorylation, photosynthesis, environmental sensing, and other vital functions in all organisms.

Therapeutics molecules are mainly linked to Transporters because drugs are vehicles from different biologic membranes. Transporters ensure the absorption and distribution roles of drugs in various kinds of tissue (placenta, kidney, central nervous system).

All actors involved in life science projects can benefit from purified membrane proteins: pharmaceutical companies, biotechnology companies, and academic research centers.

Our Transporters are most suited for these types of life science projects:

  • Drug Discovery
  • Antibody Discovery
  • Vaccine Discovery
  • Immunoassays

Transporters applications 

Eurofins CALIXAR’s Transporters are powerful therapeutic targets for projects of multi-drug resistance studies involving bacterial resistance to antibiotics.

With Eurofins CALIXAR’s Transporters, our clients can develop and validate new molecules and therapeutics antibodies. These targets are produced full-length and by maintaining their integral functions and conformity which allow them to obtain the best results in terms of development and validation of drugs.

Thanks to their high purity and stability, CALIXAR’s Transporters can avoid interferences in discovery programs due to less pure and functional membrane proteins.

Secure and boost
your discovery programs

Starting from native material or recombinant systems, we succeed with all types of proteins: Kinases, Phosphatases, Ubiquitins, Epigenetic Proteins, GPCRs, Ion Channels, Transporters, Receptors and Viral Proteins.