NLK, active
N-terminal 6His-tagged recombinant, human NLK amino acids 121-end.
Biological information
Background
NLK (Nemo Like Kinase) regulates a number of transcription factors with key roles in cell fate determination. It enables ubiquitin protein ligase binding activity and Iinvolved in protein stabilization and transforming growth factor beta receptor signaling pathway. It predicted to be located in cytosol and nucleoplasm, and to be active in cytoplasm and nucleus.
GenBank NM_016231
Target class
Kinase
Family
CMGC
Accession number
NM_016231.4
Target Name
NLK, active
Target Alias
NLK, DKFZp761G1211, FLJ21033, LAK1
Origin
Human
Theori. MW
48.7 kDa
Affinity tag
6His
Product specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Refer to CoA for Purity
Purification method
Ni2+/NTA-agarose
Sample Buffer
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only
Chemical data
Background
NLK (Nemo Like Kinase) regulates a number of transcription factors with key roles in cell fate determination. It enables ubiquitin protein ligase binding activity and Iinvolved in protein stabilization and transforming growth factor beta receptor signaling pathway. It predicted to be located in cytosol and nucleoplasm, and to be active in cytoplasm and nucleus.
GenBank NM_016231
Compound name
Kinase
Catalog number
14-676
Molecular formula
CAS
MW
Ka
Percent composition
Product specifications
Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Datasheets
14-676
Datasheet