PI3 Kinase (p110α/p85α), active
Complex of N-terminal 6His-tagged recombinant, human full length p110α and untagged recombinant, human full length p85α.
No items found.
Biological information
Background
Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers.
GenBank U79143 / GenBank XM_043865
Target class
Kinase
Family
PI3K/PI4K
Accession number
NM_006218.2
Target Name
PI3 Kinase (p110α/p85α), active
Target Alias
PIK3CA, PI3K, MGC142161, p110-alpha, MGC142163
Origin
Human
Theori. MW
125.3 kDa (p110α), 83.7 kDa (p85α)
Affinity tag
6His
Product specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Refer to CoA for Purity
Purification method
Ni2+/NTA-agarose
Sample Buffer
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only
Chemical data
Background
Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers.
GenBank U79143 / GenBank XM_043865
Compound name
Kinase
Catalog number
14-602
Molecular formula
CAS
MW
Ka
Percent composition
Product specifications
Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Datasheets
14-602
Datasheet