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Recombinant Kinase Proteins

Our collection of Recombinant Kinase Proteins offers high-quality, functionally active enzymes critical for dissecting cellular signaling pathways and developing novel inhibitors. Produced using insect, mammalian, or bacterial expression systems, our kinases provide precise enzymatic activity and consistent reproducibility to meet the rigorous demands of advanced scientific research and pharmaceutical development.

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Target
Description
Price
MAP4K5, active Human Recombinant Kinase Protein
Protein Serine/Threonine Kinases
All
10 µg of active MAP4K5. N-terminal GST-tagged, recombinant, full length, human MAP4K5.
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€ 389,00 EUR
N-terminal GST tagged and C-terminal 6His tagged, recombinant, human MAP4K4 amino acids 1-328, expressed by baculovirus in Sf21 insect cells. Purified using immobilized metal affinity chromatography.
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€ 389,00 EUR
50 µg of unactive recombinant human MAPKAP Kinase 2 (MAPKAP-K2), amino acids 46-400, A399G, containing an N-terminal GST tag.
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€ 389,00 EUR
10 µg of active recombinant human MAPKAP Kinase 2, amino acids 46-400, A399G, containing an N-terminal GST tag.
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€ 389,00 EUR
N-terminal GST-tagged recombinant, human MAPKAP Kinase 3 amino acids 2-end; activated using SAPK2a (Catalog #14-587).
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€ 389,00 EUR
N-terminal GST-tagged recombinant, human MAPKAP Kinase 3 amino acids 2-end.
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€ 389,00 EUR
N-terminal 6His-tagged recombinant, human MARK1 amino acids 2-end.
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€ 389,00 EUR
10 µg of active MARK3. N-Terminal GST-tagged, recombinant, human MARK3 full length.
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€ 389,00 EUR
10 µg of active MARK4. N-Terminal GST-tagged, recombinant, human MARK4 full length.
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€ 689,00 EUR
10 µg of active MATK. C-terminal 6His-tagged, recombinant, human MATK full length.
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€ 389,00 EUR
N-terminal GST and C-terminal 6His-tagged recombinant, human full length MEK1.
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€ 389,00 EUR
N-terminal GST-tagged and C-terminal 6His-tagged recombinant, human full length MEK1.
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€ 389,00 EUR
N-terminal 6His-tagged recombinant, human full length MEK2.
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€ 389,00 EUR
N-terminal 6His-tagged recombinant, human full length MEK2.
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€ 389,00 EUR
N-terminal 6His-tagged recombinant, human full length MEKK2.
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€ 389,00 EUR
10 µg of active MEKK3. N-terminal GST-tagged, recombinant, human MEKK3 full length.
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€ 389,00 EUR
10 µg of active MELK.Recombinant human MELK (amino acids 1 - 340), containing an N-terminal GST tag.
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€ 389,00 EUR
N-terminal 6His-tagged recombinant, human Met amino acids 974–end.
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€ 389,00 EUR
N-terminal GST-tagged recombinant, human Mer amino acids 557-882.
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€ 389,00 EUR
N-terminal 6His-tagged recombinant, human Met amino acids 974-end, containing the mutation M1268T. Met M1268T is a somatic mutation that has been identified in patients with papillary renal carcinomas (HPRC). In vitro studies have demonstrated enhanced kinase activity from this mutant.
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€ 389,00 EUR

Recombinant Kinase Proteins Key Features and Benefits

Extensive Kinase Portfolio - Explore a diverse catalog that includes active, inactive, and mutant kinases spanning various families tyrosine, serine/threonine, lipid kinases, and more designed for both fundamental research and drug discovery applications.

Optimized Expression Systems - Our proteins are produced using carefully selected expression systems to ensure correct folding and post-translational modifications, which are critical for accurate enzymatic function and assay performance.

High-Quality Assurance - Careful performance optimization and rigorous quality control procedures are implemented to guarantee the highest specific activity, and consistency from one batch to another, ensuring reliable and reproducible results.

Variety of Sizes - The product line offers flexibility with multiple packaging sizes and bulk options. Whether you need enzymes for a one-time experiment or a large-scale high-throughput screening (HTS) campaign, there are sizing options to meet your specific requirements.

Versatile Research Applications

Drug Discovery - Screen and optimize kinase inhibitors with high-precision binding and inhibition studies.

Signaling Pathway Analysis - Decode kinase regulation and mutation effects in complex cellular networks.

High-Throughput Screening - Enable large-scale inhibitor or activator screening with custom assay designs.

Structure-Function Studies: - Investigate kinase-ligand interactions and conformational dynamics with confidence.

Customize Your Assays with ADP Hunter Plus

Maximize control by pairing our recombinant kinases with ADP Hunter Plus detection reagents. This powerful combination lets you build tailored kinase activity assays, fine-tuning substrate concentrations, ATP levels, reaction timing, and kinetic parameters. Ideal for optimizing high-throughput screening (HTS) in multi-well formats or diving deep into mechanistic hypotheses, this modular approach delivers the precision and sensitivity your research demands.

All-in-One Alternative: HitHunter Kinase Enzyme Activity Assay Kits

Prefer a ready-to-use solution? Our Complete HitHunter Kinase Enzyme Activity Assay Kits provide everything you need in one validated package—recombinant kinases, matched substrates, detection reagents, and buffers. Engineered for high specificity and sensitivity, these kits support low- to high-throughput screening (HTS), with a robust ADP detection platform tolerant to elevated ATP levels (up to 1 mM).

Customized Solutions: Tailored Kinase Development

Need a purified recombinant kinase that is currently unavailable or required in a customized format? Our Custom Development Services craft recombinant kinases to your exact specifications. From rare, understudied kinases or specific recombinant configurations to custom mutations, our experts partner with you to deliver tailored enzymes that push your research and drug discovery forward.

Advance Your Research with Recombinant Kinases

Take your kinase studies to the next level—order our Recombinant Kinase Proteins today and unlock unparalleled research potential. For tailored solutions, fill out our Design Your Project Form or Contact Us to connect with our kinase specialists and accelerate your next breakthrough.

Secure and boost
your discovery programs

Starting from native material or recombinant systems, we succeed with all types of proteins: Kinases, Phosphatases, Ubiquitins, Epigenetic Proteins, GPCRs, Ion Channels, Transporters, Receptors and Viral Proteins.