STK32A, active
N-terminal 6His-tagged recombinant, human STK32A full length.
No items found.
Biological information
Background
STK32A (Serine/Threonine Kinase 32A) is a serine/threonine protein kinase that is expressed in a variety of tissues, including the brain, liver, and heart. STK32A has been implicated in the regulation of several cellular processes, including cell proliferation, cell survival, and autophagy. Research has suggested that STK32A may play a role in the development and progression of cancer. STK32A has been shown to be overexpressed in several types of cancer, including lung cancer, breast cancer, and ovarian cancer, and high levels of STK32A expression have been associated with poor prognosis. Additionally, STK32A has been suggested as a potential therapeutic target in cancer, and efforts to develop small-molecule inhibitors of the kinase are underway.
Target class
Kinase
Family
AGC
Accession number
NM_001112724.1
Target Name
STK32A, active
Target Alias
Origin
Human
Theori. MW
50 kDa
Affinity tag
6His
Product specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Purity 85% by SDS-PAGE and Coomassie blue
staining.
Purification method
Immobilised metal affinity chromatography
Sample Buffer
Protein in 50mM Tris/HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
1 year at -70°C
Usage disclaimer
For Research Only
Chemical data
Background
STK32A (Serine/Threonine Kinase 32A) is a serine/threonine protein kinase that is expressed in a variety of tissues, including the brain, liver, and heart. STK32A has been implicated in the regulation of several cellular processes, including cell proliferation, cell survival, and autophagy. Research has suggested that STK32A may play a role in the development and progression of cancer. STK32A has been shown to be overexpressed in several types of cancer, including lung cancer, breast cancer, and ovarian cancer, and high levels of STK32A expression have been associated with poor prognosis. Additionally, STK32A has been suggested as a potential therapeutic target in cancer, and efforts to develop small-molecule inhibitors of the kinase are underway.
Compound name
Kinase
Catalog number
16-011
Molecular formula
CAS
MW
Ka
Percent composition
Product specifications
Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Lipid Kinase Activity Assay Biological information
Background
STK32A (Serine/Threonine Kinase 32A) is a serine/threonine protein kinase that is expressed in a variety of tissues, including the brain, liver, and heart. STK32A has been implicated in the regulation of several cellular processes, including cell proliferation, cell survival, and autophagy. Research has suggested that STK32A may play a role in the development and progression of cancer. STK32A has been shown to be overexpressed in several types of cancer, including lung cancer, breast cancer, and ovarian cancer, and high levels of STK32A expression have been associated with poor prognosis. Additionally, STK32A has been suggested as a potential therapeutic target in cancer, and efforts to develop small-molecule inhibitors of the kinase are underway.
Target class
Kinase
Family
AGC
Subfamily
Protein Name
STK32A
Protein Alias
Accession Number
NM_001112724.1
UniProt Number
Gene Name
Gene ID
Gene Aliases
Target Species
Human
Lipid Kinase Activity Assay Usage
Product Type
Application
Storage Conditions
1 year at -70°C
Usage disclaimer
Lipid Kinase Activity Assay Information
Assay Type
Assay Measures