ULK2, active Human Recombinant Kinase Protein
10 µg of active ULK2. N-terminal GST and C-terminal 6His-tagged recombinant, human, ULK2 amino acids 1–306.
No items found.
Biological information
Background
ULK2 (Unc-51 Like Autophagy Activating Kinase 2) is a Serine/threonine-protein kinase involved in autophagy in response to starvation. The structure of this protein is similar to the C. elegans protein in that both proteins have an N-terminal kinase domain, a central proline/serine rich (PS) domain, and a C-terminal (C) domain. The gene is located within the Smith-Magenis syndrome region on chromosome 17.
GenBank NM_014683
Target class
Kinase
Family
Other
Accession number
NM_014683
Target Name
ULK2, active Human Recombinant Kinase Protein
Target Alias
ULK2
Origin
Human
Theori. MW
62 kDa
Affinity tag
GST, 6His
Product specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Refer to CoA for Purity
Purification method
Glutathione agarose affinity chromatography
Sample Buffer
Protein in 50mM Tris/HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only
Chemical data
Background
ULK2 (Unc-51 Like Autophagy Activating Kinase 2) is a Serine/threonine-protein kinase involved in autophagy in response to starvation. The structure of this protein is similar to the C. elegans protein in that both proteins have an N-terminal kinase domain, a central proline/serine rich (PS) domain, and a C-terminal (C) domain. The gene is located within the Smith-Magenis syndrome region on chromosome 17.
GenBank NM_014683
Compound name
Kinase
Catalog number
14-772
Molecular formula
CAS
MW
Ka
Percent composition
Product specifications
Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Lipid Kinase Activity Assay Biological information
Background
ULK2 (Unc-51 Like Autophagy Activating Kinase 2) is a Serine/threonine-protein kinase involved in autophagy in response to starvation. The structure of this protein is similar to the C. elegans protein in that both proteins have an N-terminal kinase domain, a central proline/serine rich (PS) domain, and a C-terminal (C) domain. The gene is located within the Smith-Magenis syndrome region on chromosome 17.
GenBank NM_014683
Target class
Kinase
Family
Other
Subfamily
Protein Name
ULK2
Protein Alias
ULK2
Accession Number
NM_014683
UniProt Number
Gene Name
Gene ID
Gene Aliases
Target Species
Human
Lipid Kinase Activity Assay Usage
Product Type
Application
Storage Conditions
6 months at -70°C
Usage disclaimer
Lipid Kinase Activity Assay Information
Assay Type
Assay Measures