Txk, active
N-terminal 6His-tagged recombinant, human Txk, amino acids 256-end.
No items found.
Biological information
Background
TxK (TxK Tyrosine Kinase) is a ,on-receptor tyrosine kinase that plays a redundant role with ITK in regulation of the adaptive immune response. It predicted to enable non-membrane spanning protein tyrosine kinase activity. TXK is also involved in positive regulation of interferon-gamma-mediated signaling pathway, positive regulation of macromolecule metabolic process, and protein autophosphorylation. TXK is located in cytoplasm and nucleus.
GenBank NM_003328
Target class
Kinase
Family
TK
Accession number
NM_003328
Target Name
Txk, active
Target Alias
TXK, PTK4
Origin
Human
Theori. MW
35.3 kDa
Affinity tag
6His
Product specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Refer to CoA for Purity
Purification method
Ni2+/NTA-agarose
Sample Buffer
Protein in 50mM Tris/HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only
Chemical data
Background
TxK (TxK Tyrosine Kinase) is a ,on-receptor tyrosine kinase that plays a redundant role with ITK in regulation of the adaptive immune response. It predicted to enable non-membrane spanning protein tyrosine kinase activity. TXK is also involved in positive regulation of interferon-gamma-mediated signaling pathway, positive regulation of macromolecule metabolic process, and protein autophosphorylation. TXK is located in cytoplasm and nucleus.
GenBank NM_003328
Compound name
Kinase
Catalog number
14-761
Molecular formula
CAS
MW
Ka
Percent composition
Product specifications
Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Lipid Kinase Activity Assay Biological information
Background
TxK (TxK Tyrosine Kinase) is a ,on-receptor tyrosine kinase that plays a redundant role with ITK in regulation of the adaptive immune response. It predicted to enable non-membrane spanning protein tyrosine kinase activity. TXK is also involved in positive regulation of interferon-gamma-mediated signaling pathway, positive regulation of macromolecule metabolic process, and protein autophosphorylation. TXK is located in cytoplasm and nucleus.
GenBank NM_003328
Target class
Kinase
Family
TK
Subfamily
Protein Name
Txk
Protein Alias
TXK, PTK4
Accession Number
NM_003328
UniProt Number
Gene Name
Gene ID
Gene Aliases
Target Species
Human
Lipid Kinase Activity Assay Usage
Product Type
Application
Storage Conditions
6 months at -70°C
Usage disclaimer
Lipid Kinase Activity Assay Information
Assay Type
Assay Measures