TAO1, active
N-terminal 6His-tagged recombinant, human TAO1 amino acids 1-327.
No items found.
Biological information
Background
TAO1 is a Serine/threonine-protein kinase involved in various processes such as p38/MAPK14 stress-activated MAPK cascade, DNA damage response and regulation of cytoskeleton stability. TAO1 enables alpha-tubulin binding activity, beta-tubulin binding activity, and kinase activity. It is also Involved in several processes, including mitotic G2 DNA damage checkpoint signaling, negative regulation of microtubule depolymerization, and positive regulation of JNK cascade.
GenBank NM_020791
Target class
Kinase
Family
STE
Accession number
NM_020791.1
Target Name
TAO1, active
Target Alias
TAOK1, MAP3K16, KIAA1361, PSK2, MARKK, FLJ14314, hKFC-B
Origin
Human
Theori. MW
41 kDa
Affinity tag
6His
Product specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Purity 93% by SDS PAGE and Coomassie blue staining
Purification method
Ni2+/NTA-agarose
Sample Buffer
Protein in 50 mM Tris/HCl pH7.5, 300 mM NaCl, 0.1 mM EGTA, 0.03% Brij 35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only
Chemical data
Background
TAO1 is a Serine/threonine-protein kinase involved in various processes such as p38/MAPK14 stress-activated MAPK cascade, DNA damage response and regulation of cytoskeleton stability. TAO1 enables alpha-tubulin binding activity, beta-tubulin binding activity, and kinase activity. It is also Involved in several processes, including mitotic G2 DNA damage checkpoint signaling, negative regulation of microtubule depolymerization, and positive regulation of JNK cascade.
GenBank NM_020791
Compound name
Kinase
Catalog number
14-749
Molecular formula
CAS
MW
Ka
Percent composition
Product specifications
Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Lipid Kinase Activity Assay Biological information
Background
TAO1 is a Serine/threonine-protein kinase involved in various processes such as p38/MAPK14 stress-activated MAPK cascade, DNA damage response and regulation of cytoskeleton stability. TAO1 enables alpha-tubulin binding activity, beta-tubulin binding activity, and kinase activity. It is also Involved in several processes, including mitotic G2 DNA damage checkpoint signaling, negative regulation of microtubule depolymerization, and positive regulation of JNK cascade.
GenBank NM_020791
Target class
Kinase
Family
STE
Subfamily
Protein Name
TAO1
Protein Alias
TAOK1, MAP3K16, KIAA1361, PSK2, MARKK, FLJ14314, hKFC-B
Accession Number
NM_020791.1
UniProt Number
Gene Name
Gene ID
Gene Aliases
Target Species
Human
Lipid Kinase Activity Assay Usage
Product Type
Application
Storage Conditions
6 months at -70°C
Usage disclaimer
Lipid Kinase Activity Assay Information
Assay Type
Assay Measures