PRKX, active
N-terminal 6His-tagged recombinant, human full length PRKX.
No items found.
Biological information
Background
PRKX (Protein Kinase X-Linked) is regulated by and mediating cAMP signaling in cells. It acts through phosphorylation of downstream targets that may include CREB, SMAD6 and PKD1 and has multiple functions in cellular differentiation and epithelial morphogenesis. It also regulates myeloid cell differentiation through SMAD6 phosphorylation. In addition, PRKX is involved in nephrogenesis by stimulating renal epithelial cell migration and tubulogenesis, and slso involved in angiogenesis through stimulation of endothelial cell proliferation, migration and vascular-like structure formation.
GenBank NM_005044
Target class
Kinase
Family
AGC
Accession number
NM_005044.2
Target Name
PRKX, active
Target Alias
PRKX, PKX1
Origin
Human
Theori. MW
44.7 kDa
Affinity tag
6His
Product specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Refer to CoA for Purity
Purification method
Ni2+/NTA-agarose
Sample Buffer
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only
Chemical data
Background
PRKX (Protein Kinase X-Linked) is regulated by and mediating cAMP signaling in cells. It acts through phosphorylation of downstream targets that may include CREB, SMAD6 and PKD1 and has multiple functions in cellular differentiation and epithelial morphogenesis. It also regulates myeloid cell differentiation through SMAD6 phosphorylation. In addition, PRKX is involved in nephrogenesis by stimulating renal epithelial cell migration and tubulogenesis, and slso involved in angiogenesis through stimulation of endothelial cell proliferation, migration and vascular-like structure formation.
GenBank NM_005044
Compound name
Kinase
Catalog number
14-677
Molecular formula
CAS
MW
Ka
Percent composition
Product specifications
Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Lipid Kinase Activity Assay Biological information
Background
PRKX (Protein Kinase X-Linked) is regulated by and mediating cAMP signaling in cells. It acts through phosphorylation of downstream targets that may include CREB, SMAD6 and PKD1 and has multiple functions in cellular differentiation and epithelial morphogenesis. It also regulates myeloid cell differentiation through SMAD6 phosphorylation. In addition, PRKX is involved in nephrogenesis by stimulating renal epithelial cell migration and tubulogenesis, and slso involved in angiogenesis through stimulation of endothelial cell proliferation, migration and vascular-like structure formation.
GenBank NM_005044
Target class
Kinase
Family
AGC
Subfamily
Protein Name
PrKX
Protein Alias
PRKX, PKX1
Accession Number
NM_005044.2
UniProt Number
Gene Name
Gene ID
Gene Aliases
Target Species
Human
Lipid Kinase Activity Assay Usage
Product Type
Application
Storage Conditions
6 months at -70°C
Usage disclaimer
Lipid Kinase Activity Assay Information
Assay Type
Assay Measures