RIPK2, active
N-terminal 6His-tagged recombinant, human RIPK2 amino acids 1-299.
No items found.
Biological information
Background
RIPK2 (receptor-interacting serine-threonine kinase 2, RIP2, RICK, CARD3, CARDIAK) is a death domain-containing serine-threonine kinase associated with TNF receptor and implicated in the activation of NF-kappaB and cell death in mammalian cells. RIPK2 represents a kinase that regulates TNF and Fas induced-apoptosis and that is involved in the generation of proinflammatory cytokine IL-1β.
GenBank NM_003821
Target class
Kinase
Family
TKL
Accession number
NM_003821.5
Target Name
RIPK2, active
Target Alias
RIPK2, RIP2, GIG30, RICK, CARDIAK, CARD3, CCK, RIP-2
Origin
Human
Theori. MW
37.8 kDa
Affinity tag
6His
Product specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Refer to CoA for Purity
Purification method
Ni2+/NTA-agarose
Sample Buffer
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only
Chemical data
Background
RIPK2 (receptor-interacting serine-threonine kinase 2, RIP2, RICK, CARD3, CARDIAK) is a death domain-containing serine-threonine kinase associated with TNF receptor and implicated in the activation of NF-kappaB and cell death in mammalian cells. RIPK2 represents a kinase that regulates TNF and Fas induced-apoptosis and that is involved in the generation of proinflammatory cytokine IL-1β.
GenBank NM_003821
Compound name
Kinase
Catalog number
14-612
Molecular formula
CAS
MW
Ka
Percent composition
Product specifications
Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Lipid Kinase Activity Assay Biological information
Background
RIPK2 (receptor-interacting serine-threonine kinase 2, RIP2, RICK, CARD3, CARDIAK) is a death domain-containing serine-threonine kinase associated with TNF receptor and implicated in the activation of NF-kappaB and cell death in mammalian cells. RIPK2 represents a kinase that regulates TNF and Fas induced-apoptosis and that is involved in the generation of proinflammatory cytokine IL-1β.
GenBank NM_003821
Target class
Kinase
Family
TKL
Subfamily
Protein Name
RIPK2
Protein Alias
RIPK2, RIP2, GIG30, RICK, CARDIAK, CARD3, CCK, RIP-2
Accession Number
NM_003821.5
UniProt Number
Gene Name
Gene ID
Gene Aliases
Target Species
Human
Lipid Kinase Activity Assay Usage
Product Type
Application
Storage Conditions
6 months at -70°C
Usage disclaimer
Lipid Kinase Activity Assay Information
Assay Type
Assay Measures