Rse, active
N-terminal 6His-tagged recombinant, human Rse, amino acids 451-end.
No items found.
Biological information
Background
Rse (TYRO3 protein tyrosine kinase), also known as Brt, BYK, Dtk, Etk3, Sky, Tif, or even sea-related receptor tyrosine kinase, is a receptor tyrosine kinase with homology to Axl. Rse is widely expressed in the adult and present in variable amounts in neural, lymphoid, vascular, and reproductive tissues. It plays a role in PI-3 kinase signaling and clearance of apoptotic cells. Gas6 acts directly on mature osteoclasts through activation of Tyro 3 and p42/p44 MAPK, possibly contributing to the bone loss by estrogen deficiency.
GenBank D17517
Target class
Kinase
Family
TK
Accession number
NM_006293.2
Target Name
Rse, active
Target Alias
TYRO3, Brt, Sky, BYK, DTK, RSE, Tif, Dtk, SKY
Origin
Human
Theori. MW
50.4 kDa
Affinity tag
6His
Product specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Refer to CoA for Purity
Purification method
Ni2+/NTA-agarose
Sample Buffer
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only
Chemical data
Background
Rse (TYRO3 protein tyrosine kinase), also known as Brt, BYK, Dtk, Etk3, Sky, Tif, or even sea-related receptor tyrosine kinase, is a receptor tyrosine kinase with homology to Axl. Rse is widely expressed in the adult and present in variable amounts in neural, lymphoid, vascular, and reproductive tissues. It plays a role in PI-3 kinase signaling and clearance of apoptotic cells. Gas6 acts directly on mature osteoclasts through activation of Tyro 3 and p42/p44 MAPK, possibly contributing to the bone loss by estrogen deficiency.
GenBank D17517
Compound name
Kinase
Catalog number
14-535
Molecular formula
CAS
MW
Ka
Percent composition
Product specifications
Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Lipid Kinase Activity Assay Biological information
Background
Rse (TYRO3 protein tyrosine kinase), also known as Brt, BYK, Dtk, Etk3, Sky, Tif, or even sea-related receptor tyrosine kinase, is a receptor tyrosine kinase with homology to Axl. Rse is widely expressed in the adult and present in variable amounts in neural, lymphoid, vascular, and reproductive tissues. It plays a role in PI-3 kinase signaling and clearance of apoptotic cells. Gas6 acts directly on mature osteoclasts through activation of Tyro 3 and p42/p44 MAPK, possibly contributing to the bone loss by estrogen deficiency.
GenBank D17517
Target class
Kinase
Family
TK
Subfamily
Protein Name
Rse
Protein Alias
TYRO3, Brt, Sky, BYK, DTK, RSE, Tif, Dtk, SKY
Accession Number
NM_006293.2
UniProt Number
Gene Name
Gene ID
Gene Aliases
Target Species
Human
Lipid Kinase Activity Assay Usage
Product Type
Application
Storage Conditions
6 months at -70°C
Usage disclaimer
Lipid Kinase Activity Assay Information
Assay Type
Assay Measures