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Rsk1/MAPKAP Kinase 1a, active Rat Recombinant Kinase Protein

N-terminal 6His and HA (YPYDV PDYA) tagged recombinant, rat full length RSK1 (residues 1-end).

Biological information

Background
Rsk1, also known as Ribosomal Protein S6 Kinase A1, is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. GenBank M99169
Target class
Kinase
Family
AGC
Accession number
NM_001006665.1; NM_002953.3
Target Name
Rsk1/MAPKAP Kinase 1a, active Rat Recombinant Kinase Protein
Target Alias
RPS6KA1, HU-1, RSK-1, MAPKAPK1A, RSK, pp90RSK1, p90S6K, RSK1
Origin
Rat
Theori. MW
88 kDa
Affinity tag
6His

Product specifications

Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Refer to CoA for Purity
Purification method
Ni2+/NTA-agarose
Sample Buffer
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
1 year at -70°C
Usage disclaimer
For Research Only

Chemical data

Background
Rsk1, also known as Ribosomal Protein S6 Kinase A1, is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. GenBank M99169
Compound name
Kinase
Catalog number
14-479
Molecular formula
CAS
MW
Ka
Percent composition

Product specifications

Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure

Lipid Kinase Activity Assay Biological information

Background
Rsk1, also known as Ribosomal Protein S6 Kinase A1, is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. GenBank M99169
Target class
Kinase
Family
AGC
Subfamily
Protein Name
Rsk1
Protein Alias
RPS6KA1, HU-1, RSK-1, MAPKAPK1A, RSK, pp90RSK1, p90S6K, RSK1
Accession Number
NM_001006665.1; NM_002953.3
UniProt Number
Gene Name
Gene ID
Gene Aliases
Target Species
Rat

Lipid Kinase Activity Assay Usage

Product Type
Application
Storage Conditions
1 year at -70°C
Usage disclaimer

Lipid Kinase Activity Assay Information

Assay Type
Assay Measures
Datasheets
User Manual
File N°2
€ 389,00 EUR
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