Yes, active Human Recombinant Kinase Protein
N-terminal 6His-tagged recombinant, human full length Yes..
No items found.
Biological information
Background
Src family kinases, Src, Fyn, and Yes, are expressed in numerous cell types, including neurons and muscle, and their activities are implicated in multiple signaling pathways. YES kinase is believed to play critical roles in tumor growth, angiogenesis, invasion, and dissemination. YES1 (YES) kinase has been implicated in several human cancers, such as advanced colon cancers and endometrial cancer. YES1 kinase inhibitors may be of therapeutic use in the treatment of human cancer.
GenBank M15990
Target class
Kinase
Family
TK
Accession number
NM_005433.3
Target Name
Yes, active Human Recombinant Kinase Protein
Target Alias
YES1, P61-YES, HsT441, Yes, c-yes, YES, p61-Yes
Origin
Human
Theori. MW
63 kDa
Affinity tag
6His
Product specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Refer to CoA for Purity
Purification method
Ni2+/NTA-agarose
Sample Buffer
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
1 year at -70°C
Usage disclaimer
For Research Only
Chemical data
Background
Src family kinases, Src, Fyn, and Yes, are expressed in numerous cell types, including neurons and muscle, and their activities are implicated in multiple signaling pathways. YES kinase is believed to play critical roles in tumor growth, angiogenesis, invasion, and dissemination. YES1 (YES) kinase has been implicated in several human cancers, such as advanced colon cancers and endometrial cancer. YES1 kinase inhibitors may be of therapeutic use in the treatment of human cancer.
GenBank M15990
Compound name
Kinase
Catalog number
14-478
Molecular formula
CAS
MW
Ka
Percent composition
Product specifications
Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Lipid Kinase Activity Assay Biological information
Background
Src family kinases, Src, Fyn, and Yes, are expressed in numerous cell types, including neurons and muscle, and their activities are implicated in multiple signaling pathways. YES kinase is believed to play critical roles in tumor growth, angiogenesis, invasion, and dissemination. YES1 (YES) kinase has been implicated in several human cancers, such as advanced colon cancers and endometrial cancer. YES1 kinase inhibitors may be of therapeutic use in the treatment of human cancer.
GenBank M15990
Target class
Kinase
Family
TK
Subfamily
Protein Name
Yes
Protein Alias
YES1, P61-YES, HsT441, Yes, c-yes, YES, p61-Yes
Accession Number
NM_005433.3
UniProt Number
Gene Name
Gene ID
Gene Aliases
Target Species
Human
Lipid Kinase Activity Assay Usage
Product Type
Application
Storage Conditions
1 year at -70°C
Usage disclaimer
Lipid Kinase Activity Assay Information
Assay Type
Assay Measures