SAPK4, unactive
N-terminal GST-tagged recombinant, human full length SAPK4.
No items found.
Biological information
Background
SAPK4 is a member of the mitogen-activated protein (MAP) kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. SAPK4 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as pro-inflammatory cytokines or physical stress leading to direct activation of transcription factors such as ELK1 and ATF2.
Target class
Kinase
Family
CMGC
Accession number
Y10488
Target Name
SAPK4, unactive
Target Alias
Origin
Human
Theori. MW
69 kDa
Affinity tag
GST
Product specifications
Expression system
Expressed in E. coli
Purity
Purity 96% by SDS-PAGE and Coomassie blue staining
Purification method
Glutathione Sepharose™ affinity chromatography
Sample Buffer
Protein in 50mM Tris/HCl pH7.5, 150mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 50% glycerol, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
1 year at -20°C
Usage disclaimer
For Research Only
Chemical data
Background
SAPK4 is a member of the mitogen-activated protein (MAP) kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. SAPK4 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as pro-inflammatory cytokines or physical stress leading to direct activation of transcription factors such as ELK1 and ATF2.
Compound name
Kinase
Catalog number
14-250
Molecular formula
CAS
MW
Ka
Percent composition
Product specifications
Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Lipid Kinase Activity Assay Biological information
Background
SAPK4 is a member of the mitogen-activated protein (MAP) kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. SAPK4 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as pro-inflammatory cytokines or physical stress leading to direct activation of transcription factors such as ELK1 and ATF2.
Target class
Kinase
Family
CMGC
Subfamily
Protein Name
SAPK4
Protein Alias
Accession Number
Y10488
UniProt Number
Gene Name
Gene ID
Gene Aliases
Target Species
Human
Lipid Kinase Activity Assay Usage
Product Type
Application
Storage Conditions
1 year at -20°C
Usage disclaimer
Lipid Kinase Activity Assay Information
Assay Type
Assay Measures