MAK, active
10 µg of active MAK. N-terminal GST-tagged, recombinant, human MAK full length.
Biological information
Background
MAK, also called Male Germ Cell Associated Kinase, is a serine/threonine protein kinase and is involved in cell cycle regulation. It plays a role in the transcriptional coactivation of AR and may play a role in chromosomal stability in prostate cancer cells. [provided by RefSeq, Jan 2016]
Target class
Kinase
Family
CMGC
Accession number
BC039825.1
Target Name
MAK, active
Target Alias
Male Germ Cell Associated Kinase; RP62; Serine/Threonine-Protein Kinase MAK; Testicular Secretory Protein Li 28
Origin
Human
Theori. MW
80 kDa
Affinity tag
GST
Product specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
60% by SDS-PAGE and Coomassie blue staining.
Purification method
glutathione agarose; size exclusion chromatography
Sample Buffer
0.67 mg/ml of enzyme in 50 mM Tris/HCl pH7.5, 300 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
1 year at -70°C.
Usage disclaimer
For Research Only
Chemical data
Background
MAK, also called Male Germ Cell Associated Kinase, is a serine/threonine protein kinase and is involved in cell cycle regulation. It plays a role in the transcriptional coactivation of AR and may play a role in chromosomal stability in prostate cancer cells. [provided by RefSeq, Jan 2016]
Compound name
Kinase
Catalog number
16-010
Molecular formula
CAS
MW
Ka
Percent composition
Product specifications
Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Datasheets
16-010
Datasheet