MYO3B, active
10 µg of active MYO3B. N-terminal GST-tagged, recombinant human MYO3B, amino acids 1-326.
Biological information
Background
Myosins are ATPases, activated by actin, that move along actin filaments in the cell. This class of myosins are characterized by an amino-terminal kinase domain and shown to be present in photoreceptors. Alternative splicing results in multiple transcript variants encoding different isoforms. Diseases associated with MYO3B include Deafness, Autosomal Recessive 30 and Entropion. Among its related pathways are Sensory processing of sound and PAK Pathway. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is MYO3A. [provided by RefSeq, Mar 2014]
Target class
Kinase
Family
Accession number
BC144307.1
Target Name
MYO3B, active
Target Alias
MYO3BMyosin IIIBMyosin-IIIbEC 2.7.11.1
Origin
Human
Theori. MW
64 kDa
Affinity tag
GST
Product specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
99% by SDS-PAGE and Coomassie blue staining.
Purification method
Purified using glutathione agarose.
Sample Buffer
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
1 year at -70°C.
Usage disclaimer
For Research Only
Chemical data
Background
Myosins are ATPases, activated by actin, that move along actin filaments in the cell. This class of myosins are characterized by an amino-terminal kinase domain and shown to be present in photoreceptors. Alternative splicing results in multiple transcript variants encoding different isoforms. Diseases associated with MYO3B include Deafness, Autosomal Recessive 30 and Entropion. Among its related pathways are Sensory processing of sound and PAK Pathway. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is MYO3A. [provided by RefSeq, Mar 2014]
Compound name
Kinase
Catalog number
15-008
Molecular formula
CAS
MW
Ka
Percent composition
Product specifications
Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Datasheets
15-008
Datasheet