MELK, active
10 µg of active MELK.Recombinant human MELK (amino acids 1 - 340), containing an N-terminal GST tag.
No items found.
Biological information
Background
Recombinant human MELK (amino acids 1 - 340), containing an N-terminal GST tag. Maternal embryonic leucine zipper kinase (MELK) is a conserved serine/threonine kinase involved in a variety of cellular functions, including proliferation, differentiation and apoptosis. Its levels are elevated in a number of tumour types and it may be a prognosis marker for some cancers.
Target class
Kinase
Family
CAMK
Accession number
NM_014791
Target Name
MELK, active
Target Alias
MELK
Origin
Human
Theori. MW
66 kDa
Affinity tag
GST
Product specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Refer to CoA for Purity
Purification method
Glutathione agarose affinity chromatography
Sample Buffer
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only
Chemical data
Background
Recombinant human MELK (amino acids 1 - 340), containing an N-terminal GST tag. Maternal embryonic leucine zipper kinase (MELK) is a conserved serine/threonine kinase involved in a variety of cellular functions, including proliferation, differentiation and apoptosis. Its levels are elevated in a number of tumour types and it may be a prognosis marker for some cancers.
Compound name
Kinase
Catalog number
14-909
Molecular formula
CAS
MW
Ka
Percent composition
Product specifications
Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Datasheets
14-909
Datasheet