Met (Y1248D), active
10 µg of active Met. N-terminal 6His-tagged recombinant, human Met amino acids 974-end, containing the mutation Y1248D.
No items found.
Biological information
Background
N-terminal 6His-tagged recombinant, human Met amino acids 974-end, containing the mutation Y1248D. Met Y1248D is a germline mutation that has been identified in patients with hereditary papillary renal carcinomas (HPRC). in vitro studies have demonstrated that this mutation has a moderate transforming ability.
Target class
Kinase
Family
TK
Accession number
J02958
Target Name
Met (Y1248D), active
Target Alias
MET, AUTS9, c-Met, RCCP2, HGFR
Origin
Human
Theori. MW
50.0 kDa
Affinity tag
6His
Product specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Refer to CoA for Purity
Purification method
Ni2+/NTA-agarose
Sample Buffer
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only
Chemical data
Background
N-terminal 6His-tagged recombinant, human Met amino acids 974-end, containing the mutation Y1248D. Met Y1248D is a germline mutation that has been identified in patients with hereditary papillary renal carcinomas (HPRC). in vitro studies have demonstrated that this mutation has a moderate transforming ability.
Compound name
Kinase
Catalog number
14-816
Molecular formula
CAS
MW
Ka
Percent composition
Product specifications
Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Datasheets
14-816
Datasheet