IRR, active
N-terminal 6His-tagged recombinant, human IRR amino acids 944-1266.
No items found.
Biological information
Background
IRR protein is a receptor with tyrosine-protein kinase activity. It functions as a pH sensing receptor which is activated by increased extracellular pH. It activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.
GenBank NM_014215
Target class
Kinase
Family
TK
Accession number
NM_014215.1
Target Name
IRR, active
Target Alias
INSRR, IRR
Origin
Human
Theori. MW
37.9 kDa
Affinity tag
6His
Product specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Refer to CoA for Purity
Purification method
Ni2+/NTA-agarose
Sample Buffer
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only
Chemical data
Background
IRR protein is a receptor with tyrosine-protein kinase activity. It functions as a pH sensing receptor which is activated by increased extracellular pH. It activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.
GenBank NM_014215
Compound name
Kinase
Catalog number
14-645
Molecular formula
CAS
MW
Ka
Percent composition
Product specifications
Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Datasheets
14-645
Datasheet