MST1, active
N-terminal 6His-tagged recombinant, human full length MST1.
No items found.
Biological information
Background
MST1 and MST2 contain a putative caspase cleavage site at the junction of the catalytic domain and the C-terminal region. MST is involved in a positive feedback loop in possible association with the SAPK and p38-MAPK pathways. MST1 has been shown activated in cellular apoptosis induced by a variety of stimuli. Inhibition of MST1 may inhibit Raf-1-mediated cell proliferation and result in apoptosis.
GenBank NM_006282
Target class
Kinase
Family
STE
Accession number
NM_006282.2
Target Name
MST1, active
Target Alias
STK4, DKFZp686A2068, MST-1, MST1, KRS2, YSK3
Origin
Human
Theori. MW
57 kDa
Affinity tag
6His
Product specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Refer to CoA for Purity
Purification method
Ni2+/NTA-agarose
Sample Buffer
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only
Chemical data
Background
MST1 and MST2 contain a putative caspase cleavage site at the junction of the catalytic domain and the C-terminal region. MST is involved in a positive feedback loop in possible association with the SAPK and p38-MAPK pathways. MST1 has been shown activated in cellular apoptosis induced by a variety of stimuli. Inhibition of MST1 may inhibit Raf-1-mediated cell proliferation and result in apoptosis.
GenBank NM_006282
Compound name
Kinase
Catalog number
14-624
Molecular formula
CAS
MW
Ka
Percent composition
Product specifications
Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Datasheets
14-624
Datasheet