Solubilization, stabilization, and crystallization kits

CALIXAR™ Solublization & Stabilization K1 Screening Kit

CALIXAR’s screening kit helps to find the most suitable combination of CALIXAR’s reagents to extract and stabilize membrane proteins. Reach high solubility rate, increase your protein stability for your scientific projects with accurate results to discover new drugs (small molecules, antibodies, …) and to open new therapeutic pathways.
€ 370.00

User guide and certificate of analysis will be including in your package.
You can purchase each reagent individually from our online catalog.

Information

Compound name: CALIXAR™ Screening Kit

Catalogue number: CALIXAR-K1

Including reagents:  6 proprietary mild detergents and 4 proprietary stabilization reagents

Chemical structures:  CALX8, DDTAC, DDG, DLAC, FLAC6, ODG, FTAC6, FTAC8, DDLAC, CALXGLUK

MW: 497.6 – 2582 (g/mol)

Production

Volume: CALIXAR-K1 is presented as a 10 x 100 µL microfuge tubes

For a typical 10-wells experiment: Add 250 µg of membrane protein sample, 10 µL of soft proprietary detergent and complete with buffer of choice to 50 µL.

For stabilization experiment also add 10µL of soft proprietary and stabilization reagent.

Stability: Long term storage at -20 ° C.

Solubility: Provided in solution.

Working pH: Maintain pH between 6-9 for optimal results.

What makes us special

We use proprietary technology and custom-built method to give you the edge

CALIXAR’s solubilization and stabilization screening kit helps to extract and stabilize membrane therapeutic targets (GPCRs, ion channels, transporters, enzymes, …). This kit includes 6 proprietary mild detergents and 4 proprietary stabilization reagents to improve trials and research involving membrane proteins.

With 10 tests, our screening assay kit can be used to determine the best reagent or the most suitable combination of reagents to extract, solubilize and stabilize native and functional membrane proteins in a solution.  

Thanks to these reagents, our clients can obtain pure and functional membrane proteins with high medical relevance to discover new drugs (small molecules, antibodies,  vaccines, …).

Native Full-Length Proteins

CALIXAR’s screening assay kit contains 10 proprietary mild detergents and stabilization reagents. These molecules are specifically designed to extract and stabilize membrane proteins while preserving their functionalities.

Specifically made for Biotech

CALIXAR™ Solubilization and Stabilization Screening Kit is used for research, drug discovery, and structural studies that are used in the life science fields. Particularly adapted for biotechnology companies, as well as for academic teams (structural biologists, pharmacologists, biochemists, virologists).

For any Life Science Project
  • Antibodies (including nanobodies, scaffold proteins, aptamers)
  • Small molecules
  • 3D Structures (cryoEM, XRay crystallography, NMR, SANS, SAXS)
  • Drug discovery (Screening: HTS, FBDD, SBDD; Hit and lead validation)
  • Antibody discovery (Immunization and display technologies)
  • Clinical stage (drug validation on reliable native DDLAC)
More documentation

References

ACS PUBLICATIONS

Lactobionamide Surfactants with Hydrogenated, Perfluorinated or Hemifluorinated Tails

Lebaupain F. et al. 2006
FEBS LETTERS

New tensio-active molecules stabilize a human G protein-coupled receptor in solution.

Damian, M. et al. 2007
ACS PUBLICATIONS

Glucose-Based Surfactants with Hydrogenated, Fluorinated, or Hemifluorinated Tails: Synthesis and Comparative Physical-Chemical Characterization

Abla M et al. 2008

Secure and boost
your discovery programs.

Starting from native material or recombinant systems, we succeed with all types of membrane proteins: GPCRs, Ion Channels, Transporters, Receptors and Viral Proteins.