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FLAC6
Soft proprietary detergents

FLAC6 Reagent

CALIXAR’s FLAC6 reagent is a non-ionic amphiphilic detergent / surfactant with a lactobionamide head group and a fluorinated chain.
€ 198.00 (50mg)
€ 297.00 (100mg)
€ 649.00 (250mg)
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Information

IUPAC name: (4,4,5,5,6,6,7,7,8,8,9,9,9-tridecafluorononylamine) lactobionamide

Compound name: FLAC6

Catalogue number: FLAC6_50MG
FLAC6_100MG
FLAC6_250MG,
FLAC6_500MG,
FLAC6_1G

Molec. Formula: C21H28F13NO11

CAS: nd

MW: 717.4 g/mol

pKa: na​

Percent Composition: C, 35.16; H, 3.93; F, 34.43; N, 1.95; O, 24.53

Production

Physical state: White powder

Purity (HPLC, 214nm): ≥98%

Retention time (RP18 HPLC)b: tR = 13.8 min

CMC: 0.56 mM (TS)

Exact mass: 717.1455

Stability: Store in <-20°C out of direct light

Solubility Structure: Soluble in water (28mM), methanol and DMSO

What makes us special

We use a unique & custom-produced program to provide you with an edge

CALIXAR’s FLAC6 is manufactured into a powder form and is used in an aqueous solution or buffer. FLAC6 can be combined with biological substances (biological membranes).

Our clients are able to use FLAC6 to produce lipid detergents, mixed micelles, and protein detergent micelles. FLAC6 empowers clients to extract, to solubilize and to stabilize native and functional membrane proteins in a solution.

FLAC6 is a very gentle non-ionic detergent to extract, solubilize and to stabilize native membrane proteins. As it is indifferent to ionic strength or pH variations it is ideal to extract, solubilize and stabilize particular membrane proteins of high medical relevance.

Application note
Native Full-Length Proteins

CALIXAR’s FLAC6 is non-ionic and therefore is not sensitive to ionic strength or pH variations. It is well conformed to extract, to solubilize and to stabilize specific membrane proteins.

Specifically made for Biotech

CALIXAR’s FLAC6 extracts high-quality membrane proteins used for research, pharmaceutical discovery, and structural studies. FLAC6 is designed for pharmaceutical and biotechnology companies, as-well-as for academic teams (biochemists, structural biologists, pharmacologists, virologists) that are involved in the life science fields.

For any Life Science Project
  • Antibodies (including nanobodies, scaffold proteins, aptamers)
  • Small molecules
  • 3D Structures (cryoEM, XRay crystallography, NMR, SANS, SAXS)
  • Drug discovery (Screening: HTS, FBDD, SBDD; Hit and lead validation)
  • Antibody discovery (Immunization and display technologies)
  • Clinical stage
More documentation

References

ACS PUBLICATIONS

Lactobionamide Surfactants with Hydrogenated, Perfluorinated or Hemifluorinated Tails

Lebaupain F. et al. 2006
Read more
Conformational antibody development
Vaccine development
Ligand high-throughput screening
Structure-based drug discovery
Immunoassays
Deorphanization projects
Identification of relevant targets
Expression of full-length membrane proteins
Functional isolation and stabilization of targets
Conformational antibody development
Vaccine development
High-throughput ligand screening
Structure-based drug discovery
Immunoassays
Deorphanization projects
Identification of relevant targets
Expression of full-length membrane proteins
Functional isolation and stabilization of targets

Secure and boost
your discovery programs.

Starting from native material or recombinant systems, we succeed with all types of membrane proteins: GPCRs, Ion Channels, Transporters, Receptors and Viral Proteins.

Contact us