CALIXAR’s DDLAC is produced into a powder form and is utilized in an aqueous solution or buffer. DDLAC can be mixed with biological materials (biological membranes).
Our clients are able to use DDLAC to aid in the production of lipid detergents, mixed micelles, and protein detergent micelles. DDLAC enables clients to extract, to solubilize and to stabilize native and functional membrane proteins of high medical relevance within a solution.
DDLAC is a fairly mild detergent used to solubilize and stabilize native membrane proteins that are non-ionic. Consequently, as it is not sensitive to ionic strength or pH variations, they are ideal to extract precise membrane proteins.
- Antibodies (including nanobodies, scaffold proteins, aptamers)
- Small molecules
- 3D Structures (cryoEM, XRay crystallography, NMR, SANS, SAXS)
- Drug discovery (Screening: HTS, FBDD, SBDD; Hit and lead validation)
- Antibody discovery (Immunization and display technologies)
- Clinical stage