PDHK2, active Human Recombinant Kinase Protein
10 µg of active PDHK2. N-terminal GST-tagged, recombinant, human PDHK2 full length.
No items found.
Biological information
Background
PDHK2 is a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. [provided by RefSeq, Dec 2010]
Target class
Kinase
Family
Accession number
NM_002611.3
Target Name
PDHK2, active Human Recombinant Kinase Protein
Target Alias
Pyruvate Dehydrogenase Kinase 2[Pyruvate Dehydrogenase (Acetyl-Transferring)] Kinase Isozyme 2MitochondrialPyruvate Dehydrogenase KinaseIsoenzyme 2yruvate Dehydrogenase Kinase Isoform 2PDH Kinase 2
Origin
Human
Theori. MW
73 kDa
Affinity tag
GST
Product specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
90% by SDS-PAGE and Coomassie blue staining.
Purification method
Purified using glutathione agarose.
Sample Buffer
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
1 year at -70°C.
Usage disclaimer
For Research Only
Chemical data
Background
PDHK2 is a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. [provided by RefSeq, Dec 2010]
Compound name
Kinase
Catalog number
16-038
Molecular formula
CAS
MW
Ka
Percent composition
Product specifications
Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Kinase Activity Assay Biological information
Background
PDHK2 is a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. [provided by RefSeq, Dec 2010]
Target class
Kinase
Family
Subfamily
Protein Name
PDHK2
Protein Alias
Pyruvate Dehydrogenase Kinase 2[Pyruvate Dehydrogenase (Acetyl-Transferring)] Kinase Isozyme 2MitochondrialPyruvate Dehydrogenase KinaseIsoenzyme 2yruvate Dehydrogenase Kinase Isoform 2PDH Kinase 2
Accession Number
NM_002611.3
UniProt Number
Gene Name
Gene ID
Gene Aliases
Target Species
Human
Kinase Activity Assay Usage
Product Type
Application
Storage Conditions
1 year at -70°C.
Usage disclaimer
Kinase Activity Assay Information
Assay Type
Assay Measures
Biological Information
Background
PDHK2 is a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. [provided by RefSeq, Dec 2010]
Target class
Kinase
Family
Accession Number
NM_002611.3
Target Name
PDHK2
Target Alias
Pyruvate Dehydrogenase Kinase 2[Pyruvate Dehydrogenase (Acetyl-Transferring)] Kinase Isozyme 2MitochondrialPyruvate Dehydrogenase KinaseIsoenzyme 2yruvate Dehydrogenase Kinase Isoform 2PDH Kinase 2
Origin
Human
Theoretical MW
Affinity Tag
GST
Product Specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
90% by SDS-PAGE and Coomassie blue staining.
Purification method
Purified using glutathione agarose.
Sample Buffer
Specified activity
Refer to CoA
Application
Storage conditions
1 year at -70°C.
Usage disclaimer
For Research Only
Biological Information
Background
PDHK2 is a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. [provided by RefSeq, Dec 2010]
Target class
Kinase
Family
Accession Number
NM_002611.3
Target Name
PDHK2
Target Alias
Pyruvate Dehydrogenase Kinase 2[Pyruvate Dehydrogenase (Acetyl-Transferring)] Kinase Isozyme 2MitochondrialPyruvate Dehydrogenase KinaseIsoenzyme 2yruvate Dehydrogenase Kinase Isoform 2PDH Kinase 2
Origin
Human
Theoretical MW
Affinity Tag
GST
Product Specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
90% by SDS-PAGE and Coomassie blue staining.
Purification method
Purified using glutathione agarose.
Sample Buffer
Specified activity
Refer to CoA
Application
Storage conditions
1 year at -70°C.
Usage disclaimer
For Research Only