NEK5, active Human Recombinant Kinase Protein
10 µg of active NEK5. N-terminal 6His-tagged, recombinant, human NEK5 amino acids 1-311.
No items found.
Biological information
Background
the never-in-mitosis kinase (NEK) family is emerging as novel kinase targets in various cancer types. NEK5 is an understudied member of the NEK family. While there are more recent studies describing the physiologic function of NEK5, its role in cancer biology remains widely understudied. However, emerging studies implicate that NEK5 has potentially crucial functions in various solid tumors. [provided by Alliance of Genome Resources, Apr 2022]
Target class
Kinase
Family
OTHER-NEK
Accession number
BC063885.1
Target Name
NEK5, active Human Recombinant Kinase Protein
Target Alias
NIMA Related Kinase 5; Serine/Threonine-Protein Kinase Nek5; NimA-Related Protein Kinase 5; Never In Mitosis A-Related Kinase 5
Origin
Human
Theori. MW
39.9 kDa
Affinity tag
6His
Product specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
74% by SDS-PAGE and Coomassie blue staining.
Purification method
Immobilised metal affinity chromatography
Sample Buffer
enzyme in 50 mM Tris/HCl pH 7.5, 300 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
1 year at -70°C.
Usage disclaimer
For Research Only
Chemical data
Background
the never-in-mitosis kinase (NEK) family is emerging as novel kinase targets in various cancer types. NEK5 is an understudied member of the NEK family. While there are more recent studies describing the physiologic function of NEK5, its role in cancer biology remains widely understudied. However, emerging studies implicate that NEK5 has potentially crucial functions in various solid tumors. [provided by Alliance of Genome Resources, Apr 2022]
Compound name
Kinase
Catalog number
15-037
Molecular formula
CAS
MW
Ka
Percent composition
Product specifications
Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Kinase Activity Assay Biological information
Background
the never-in-mitosis kinase (NEK) family is emerging as novel kinase targets in various cancer types. NEK5 is an understudied member of the NEK family. While there are more recent studies describing the physiologic function of NEK5, its role in cancer biology remains widely understudied. However, emerging studies implicate that NEK5 has potentially crucial functions in various solid tumors. [provided by Alliance of Genome Resources, Apr 2022]
Target class
Kinase
Family
OTHER-NEK
Subfamily
Protein Name
NEK5
Protein Alias
NIMA Related Kinase 5; Serine/Threonine-Protein Kinase Nek5; NimA-Related Protein Kinase 5; Never In Mitosis A-Related Kinase 5
Accession Number
BC063885.1
UniProt Number
Gene Name
Gene ID
Gene Aliases
Target Species
Human
Kinase Activity Assay Usage
Product Type
Application
Storage Conditions
1 year at -70°C.
Usage disclaimer
Kinase Activity Assay Information
Assay Type
Assay Measures
Biological Information
Background
the never-in-mitosis kinase (NEK) family is emerging as novel kinase targets in various cancer types. NEK5 is an understudied member of the NEK family. While there are more recent studies describing the physiologic function of NEK5, its role in cancer biology remains widely understudied. However, emerging studies implicate that NEK5 has potentially crucial functions in various solid tumors. [provided by Alliance of Genome Resources, Apr 2022]
Target class
Kinase
Family
OTHER-NEK
Accession Number
BC063885.1
Target Name
NEK5
Target Alias
NIMA Related Kinase 5; Serine/Threonine-Protein Kinase Nek5; NimA-Related Protein Kinase 5; Never In Mitosis A-Related Kinase 5
Origin
Human
Theoretical MW
Affinity Tag
6His
Product Specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
74% by SDS-PAGE and Coomassie blue staining.
Purification method
Immobilised metal affinity chromatography
Sample Buffer
Specified activity
Refer to CoA
Application
Storage conditions
1 year at -70°C.
Usage disclaimer
For Research Only
Biological Information
Background
the never-in-mitosis kinase (NEK) family is emerging as novel kinase targets in various cancer types. NEK5 is an understudied member of the NEK family. While there are more recent studies describing the physiologic function of NEK5, its role in cancer biology remains widely understudied. However, emerging studies implicate that NEK5 has potentially crucial functions in various solid tumors. [provided by Alliance of Genome Resources, Apr 2022]
Target class
Kinase
Family
OTHER-NEK
Accession Number
BC063885.1
Target Name
NEK5
Target Alias
NIMA Related Kinase 5; Serine/Threonine-Protein Kinase Nek5; NimA-Related Protein Kinase 5; Never In Mitosis A-Related Kinase 5
Origin
Human
Theoretical MW
Affinity Tag
6His
Product Specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
74% by SDS-PAGE and Coomassie blue staining.
Purification method
Immobilised metal affinity chromatography
Sample Buffer
Specified activity
Refer to CoA
Application
Storage conditions
1 year at -70°C.
Usage disclaimer
For Research Only