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MST2, active Human Recombinant Kinase Protein

N-terminal 6His-tagged recombinant, human MST2 amino acids 2-end.

Biological information

Background
Serine/threonine-protein kinase 3 STK3 (Mammalian STE20-like kinase 2, MST2, Serine/threonine-protein kinase Krs-1, ST2) has been shown to be activated in cellular apoptosis induced by a variety of stimuli. In most cases, MST2 activation during apoptosis has been reported to accompany caspase-3 cleavage of the enzyme. A few studies have also implicated protein phosphorylation reactions in MST2 regulation. GenBank U60206
Target class
Kinase
Family
STE
Accession number
NM_006281.2
Target Name
MST2, active Human Recombinant Kinase Protein
Target Alias
STK3, MST-2, FLJ90748, MST2, KRS1
Origin
Human
Theori. MW
57.2 kDa
Affinity tag
6His

Product specifications

Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Refer to CoA for Purity
Purification method
Ni2+/NTA-agarose
Sample Buffer
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only

Chemical data

Background
Serine/threonine-protein kinase 3 STK3 (Mammalian STE20-like kinase 2, MST2, Serine/threonine-protein kinase Krs-1, ST2) has been shown to be activated in cellular apoptosis induced by a variety of stimuli. In most cases, MST2 activation during apoptosis has been reported to accompany caspase-3 cleavage of the enzyme. A few studies have also implicated protein phosphorylation reactions in MST2 regulation. GenBank U60206
Compound name
Kinase
Catalog number
14-524
Molecular formula
CAS
MW
Ka
Percent composition

Product specifications

Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure

Lipid Kinase Activity Assay Biological information

Background
Serine/threonine-protein kinase 3 STK3 (Mammalian STE20-like kinase 2, MST2, Serine/threonine-protein kinase Krs-1, ST2) has been shown to be activated in cellular apoptosis induced by a variety of stimuli. In most cases, MST2 activation during apoptosis has been reported to accompany caspase-3 cleavage of the enzyme. A few studies have also implicated protein phosphorylation reactions in MST2 regulation. GenBank U60206
Target class
Kinase
Family
STE
Subfamily
Protein Name
MST2
Protein Alias
STK3, MST-2, FLJ90748, MST2, KRS1
Accession Number
NM_006281.2
UniProt Number
Gene Name
Gene ID
Gene Aliases
Target Species
Human

Lipid Kinase Activity Assay Usage

Product Type
Application
Storage Conditions
6 months at -70°C
Usage disclaimer

Lipid Kinase Activity Assay Information

Assay Type
Assay Measures

Biological Information

Background
Serine/threonine-protein kinase 3 STK3 (Mammalian STE20-like kinase 2, MST2, Serine/threonine-protein kinase Krs-1, ST2) has been shown to be activated in cellular apoptosis induced by a variety of stimuli. In most cases, MST2 activation during apoptosis has been reported to accompany caspase-3 cleavage of the enzyme. A few studies have also implicated protein phosphorylation reactions in MST2 regulation. GenBank U60206
Target class
Kinase
Family
STE
Accession Number
NM_006281.2
Target Name
MST2
Target Alias
STK3, MST-2, FLJ90748, MST2, KRS1
Origin
Human
Theoretical MW
Affinity Tag
6His

Product Specifications

Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Refer to CoA for Purity
Purification method
Ni2+/NTA-agarose
Sample Buffer
Specified activity
Refer to CoA
Application
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only

Biological Information

Background
Serine/threonine-protein kinase 3 STK3 (Mammalian STE20-like kinase 2, MST2, Serine/threonine-protein kinase Krs-1, ST2) has been shown to be activated in cellular apoptosis induced by a variety of stimuli. In most cases, MST2 activation during apoptosis has been reported to accompany caspase-3 cleavage of the enzyme. A few studies have also implicated protein phosphorylation reactions in MST2 regulation. GenBank U60206
Target class
Kinase
Family
STE
Accession Number
NM_006281.2
Target Name
MST2
Target Alias
STK3, MST-2, FLJ90748, MST2, KRS1
Origin
Human
Theoretical MW
Affinity Tag
6His

Product Specifications

Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Refer to CoA for Purity
Purification method
Ni2+/NTA-agarose
Sample Buffer
Specified activity
Refer to CoA
Application
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only
Datasheets
User Manual
File N°2
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