MST1, active Human Recombinant Kinase Protein
N-terminal 6His-tagged recombinant, human full length MST1.
No items found.
Biological information
Background
MST1 and MST2 contain a putative caspase cleavage site at the junction of the catalytic domain and the C-terminal region. MST is involved in a positive feedback loop in possible association with the SAPK and p38-MAPK pathways. MST1 has been shown activated in cellular apoptosis induced by a variety of stimuli. Inhibition of MST1 may inhibit Raf-1-mediated cell proliferation and result in apoptosis.
GenBank NM_006282
Target class
Kinase
Family
STE
Accession number
NM_006282.2
Target Name
MST1, active Human Recombinant Kinase Protein
Target Alias
STK4, DKFZp686A2068, MST-1, MST1, KRS2, YSK3
Origin
Human
Theori. MW
57 kDa
Affinity tag
6His
Product specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Refer to CoA for Purity
Purification method
Ni2+/NTA-agarose
Sample Buffer
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only
Chemical data
Background
MST1 and MST2 contain a putative caspase cleavage site at the junction of the catalytic domain and the C-terminal region. MST is involved in a positive feedback loop in possible association with the SAPK and p38-MAPK pathways. MST1 has been shown activated in cellular apoptosis induced by a variety of stimuli. Inhibition of MST1 may inhibit Raf-1-mediated cell proliferation and result in apoptosis.
GenBank NM_006282
Compound name
Kinase
Catalog number
14-624
Molecular formula
CAS
MW
Ka
Percent composition
Product specifications
Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Kinase Activity Assay Biological information
Background
MST1 and MST2 contain a putative caspase cleavage site at the junction of the catalytic domain and the C-terminal region. MST is involved in a positive feedback loop in possible association with the SAPK and p38-MAPK pathways. MST1 has been shown activated in cellular apoptosis induced by a variety of stimuli. Inhibition of MST1 may inhibit Raf-1-mediated cell proliferation and result in apoptosis.
GenBank NM_006282
Target class
Kinase
Family
STE
Subfamily
Protein Name
MST1
Protein Alias
STK4, DKFZp686A2068, MST-1, MST1, KRS2, YSK3
Accession Number
NM_006282.2
UniProt Number
Gene Name
Gene ID
Gene Aliases
Target Species
Human
Kinase Activity Assay Usage
Product Type
Application
Storage Conditions
6 months at -70°C
Usage disclaimer
Kinase Activity Assay Information
Assay Type
Assay Measures
Biological Information
Background
MST1 and MST2 contain a putative caspase cleavage site at the junction of the catalytic domain and the C-terminal region. MST is involved in a positive feedback loop in possible association with the SAPK and p38-MAPK pathways. MST1 has been shown activated in cellular apoptosis induced by a variety of stimuli. Inhibition of MST1 may inhibit Raf-1-mediated cell proliferation and result in apoptosis.
GenBank NM_006282
Target class
Kinase
Family
STE
Accession Number
NM_006282.2
Target Name
MST1
Target Alias
STK4, DKFZp686A2068, MST-1, MST1, KRS2, YSK3
Origin
Human
Theoretical MW
Affinity Tag
6His
Product Specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Refer to CoA for Purity
Purification method
Ni2+/NTA-agarose
Sample Buffer
Specified activity
Refer to CoA
Application
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only
Biological Information
Background
MST1 and MST2 contain a putative caspase cleavage site at the junction of the catalytic domain and the C-terminal region. MST is involved in a positive feedback loop in possible association with the SAPK and p38-MAPK pathways. MST1 has been shown activated in cellular apoptosis induced by a variety of stimuli. Inhibition of MST1 may inhibit Raf-1-mediated cell proliferation and result in apoptosis.
GenBank NM_006282
Target class
Kinase
Family
STE
Accession Number
NM_006282.2
Target Name
MST1
Target Alias
STK4, DKFZp686A2068, MST-1, MST1, KRS2, YSK3
Origin
Human
Theoretical MW
Affinity Tag
6His
Product Specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Refer to CoA for Purity
Purification method
Ni2+/NTA-agarose
Sample Buffer
Specified activity
Refer to CoA
Application
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only