MKK6/SKK3, unactive Human Recombinant Kinase Protein
Recombinant human MKK6 amino acids 4-end, fused at the N-terminus to a Mal-E tag.
No items found.
Biological information
Background
MKK6/SKK3 Protein is a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.
EMBL U39657
Target class
Kinase
Family
STE
Accession number
NM_002758.3
Target Name
MKK6/SKK3, unactive Human Recombinant Kinase Protein
Target Alias
MAP2K6, PRKMK6, MEK6, SAPKK3, MAPKK6, MKK6
Origin
Human
Theori. MW
80.6 kDa
Affinity tag
Mal-E
Product specifications
Expression system
Expressed in E. coli
Purity
Refer to CoA for Purity
Purification method
Amylose resin beads affinity chromatography
Sample Buffer
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only
Chemical data
Background
MKK6/SKK3 Protein is a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.
EMBL U39657
Compound name
Kinase
Catalog number
14-304
Molecular formula
CAS
MW
Ka
Percent composition
Product specifications
Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Kinase Activity Assay Biological information
Background
MKK6/SKK3 Protein is a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.
EMBL U39657
Target class
Kinase
Family
STE
Subfamily
Protein Name
MKK6
Protein Alias
MAP2K6, PRKMK6, MEK6, SAPKK3, MAPKK6, MKK6
Accession Number
NM_002758.3
UniProt Number
Gene Name
Gene ID
Gene Aliases
Target Species
Human
Kinase Activity Assay Usage
Product Type
Application
Storage Conditions
6 months at -70°C
Usage disclaimer
Kinase Activity Assay Information
Assay Type
Assay Measures
Biological Information
Background
MKK6/SKK3 Protein is a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.
EMBL U39657
Target class
Kinase
Family
STE
Accession Number
NM_002758.3
Target Name
MKK6
Target Alias
MAP2K6, PRKMK6, MEK6, SAPKK3, MAPKK6, MKK6
Origin
Human
Theoretical MW
Affinity Tag
Mal-E
Product Specifications
Expression system
Expressed in E. coli
Purity
Refer to CoA for Purity
Purification method
Amylose resin beads affinity chromatography
Sample Buffer
Specified activity
Refer to CoA
Application
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only
Biological Information
Background
MKK6/SKK3 Protein is a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.
EMBL U39657
Target class
Kinase
Family
STE
Accession Number
NM_002758.3
Target Name
MKK6
Target Alias
MAP2K6, PRKMK6, MEK6, SAPKK3, MAPKK6, MKK6
Origin
Human
Theoretical MW
Affinity Tag
Mal-E
Product Specifications
Expression system
Expressed in E. coli
Purity
Refer to CoA for Purity
Purification method
Amylose resin beads affinity chromatography
Sample Buffer
Specified activity
Refer to CoA
Application
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only