Met (Y1248D), active Human Recombinant Kinase Protein
10 µg of active Met. N-terminal 6His-tagged recombinant, human Met amino acids 974-end, containing the mutation Y1248D.
No items found.
Biological information
Background
N-terminal 6His-tagged recombinant, human Met amino acids 974-end, containing the mutation Y1248D. Met Y1248D is a germline mutation that has been identified in patients with hereditary papillary renal carcinomas (HPRC). in vitro studies have demonstrated that this mutation has a moderate transforming ability.
Target class
Kinase
Family
TK
Accession number
J02958
Target Name
Met (Y1248D), active Human Recombinant Kinase Protein
Target Alias
MET, AUTS9, c-Met, RCCP2, HGFR
Origin
Human
Theori. MW
50.0 kDa
Affinity tag
6His
Product specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Refer to CoA for Purity
Purification method
Ni2+/NTA-agarose
Sample Buffer
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only
Chemical data
Background
N-terminal 6His-tagged recombinant, human Met amino acids 974-end, containing the mutation Y1248D. Met Y1248D is a germline mutation that has been identified in patients with hereditary papillary renal carcinomas (HPRC). in vitro studies have demonstrated that this mutation has a moderate transforming ability.
Compound name
Kinase
Catalog number
14-816
Molecular formula
CAS
MW
Ka
Percent composition
Product specifications
Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Kinase Activity Assay Biological information
Background
N-terminal 6His-tagged recombinant, human Met amino acids 974-end, containing the mutation Y1248D. Met Y1248D is a germline mutation that has been identified in patients with hereditary papillary renal carcinomas (HPRC). in vitro studies have demonstrated that this mutation has a moderate transforming ability.
Target class
Kinase
Family
TK
Subfamily
Protein Name
Met
Protein Alias
MET, AUTS9, c-Met, RCCP2, HGFR
Accession Number
J02958
UniProt Number
Gene Name
Gene ID
Gene Aliases
Target Species
Human
Kinase Activity Assay Usage
Product Type
Application
Storage Conditions
6 months at -70°C
Usage disclaimer
Kinase Activity Assay Information
Assay Type
Assay Measures
Biological Information
Background
N-terminal 6His-tagged recombinant, human Met amino acids 974-end, containing the mutation Y1248D. Met Y1248D is a germline mutation that has been identified in patients with hereditary papillary renal carcinomas (HPRC). in vitro studies have demonstrated that this mutation has a moderate transforming ability.
Target class
Kinase
Family
TK
Accession Number
J02958
Target Name
Met
Target Alias
MET, AUTS9, c-Met, RCCP2, HGFR
Origin
Human
Theoretical MW
Affinity Tag
6His
Product Specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Refer to CoA for Purity
Purification method
Ni2+/NTA-agarose
Sample Buffer
Specified activity
Refer to CoA
Application
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only
Biological Information
Background
N-terminal 6His-tagged recombinant, human Met amino acids 974-end, containing the mutation Y1248D. Met Y1248D is a germline mutation that has been identified in patients with hereditary papillary renal carcinomas (HPRC). in vitro studies have demonstrated that this mutation has a moderate transforming ability.
Target class
Kinase
Family
TK
Accession Number
J02958
Target Name
Met
Target Alias
MET, AUTS9, c-Met, RCCP2, HGFR
Origin
Human
Theoretical MW
Affinity Tag
6His
Product Specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Refer to CoA for Purity
Purification method
Ni2+/NTA-agarose
Sample Buffer
Specified activity
Refer to CoA
Application
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only