MAK, active Human Recombinant Kinase Protein
10 µg of active MAK. N-terminal GST-tagged, recombinant, human MAK full length.
Biological information
Background
MAK, also called Male Germ Cell Associated Kinase, is a serine/threonine protein kinase and is involved in cell cycle regulation. It plays a role in the transcriptional coactivation of AR and may play a role in chromosomal stability in prostate cancer cells. [provided by RefSeq, Jan 2016]
Target class
Kinase
Family
CMGC
Accession number
BC039825.1
Target Name
MAK, active Human Recombinant Kinase Protein
Target Alias
Male Germ Cell Associated Kinase; RP62; Serine/Threonine-Protein Kinase MAK; Testicular Secretory Protein Li 28
Origin
Human
Theori. MW
80 kDa
Affinity tag
GST
Product specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
60% by SDS-PAGE and Coomassie blue staining.
Purification method
glutathione agarose; size exclusion chromatography
Sample Buffer
0.67 mg/ml of enzyme in 50 mM Tris/HCl pH7.5, 300 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
1 year at -70°C.
Usage disclaimer
For Research Only
Chemical data
Background
MAK, also called Male Germ Cell Associated Kinase, is a serine/threonine protein kinase and is involved in cell cycle regulation. It plays a role in the transcriptional coactivation of AR and may play a role in chromosomal stability in prostate cancer cells. [provided by RefSeq, Jan 2016]
Compound name
Kinase
Catalog number
16-010
Molecular formula
CAS
MW
Ka
Percent composition
Product specifications
Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Kinase Activity Assay Biological information
Background
MAK, also called Male Germ Cell Associated Kinase, is a serine/threonine protein kinase and is involved in cell cycle regulation. It plays a role in the transcriptional coactivation of AR and may play a role in chromosomal stability in prostate cancer cells. [provided by RefSeq, Jan 2016]
Target class
Kinase
Family
CMGC
Subfamily
Protein Name
MAK
Protein Alias
Male Germ Cell Associated Kinase; RP62; Serine/Threonine-Protein Kinase MAK; Testicular Secretory Protein Li 28
Accession Number
BC039825.1
UniProt Number
Gene Name
Gene ID
Gene Aliases
Target Species
Human
Kinase Activity Assay Usage
Product Type
Application
Storage Conditions
1 year at -70°C.
Usage disclaimer
Kinase Activity Assay Information
Assay Type
Assay Measures
Biological Information
Background
MAK, also called Male Germ Cell Associated Kinase, is a serine/threonine protein kinase and is involved in cell cycle regulation. It plays a role in the transcriptional coactivation of AR and may play a role in chromosomal stability in prostate cancer cells. [provided by RefSeq, Jan 2016]
Target class
Kinase
Family
CMGC
Accession Number
BC039825.1
Target Name
MAK
Target Alias
Male Germ Cell Associated Kinase; RP62; Serine/Threonine-Protein Kinase MAK; Testicular Secretory Protein Li 28
Origin
Human
Theoretical MW
Affinity Tag
GST
Product Specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
60% by SDS-PAGE and Coomassie blue staining.
Purification method
glutathione agarose; size exclusion chromatography
Sample Buffer
Specified activity
Refer to CoA
Application
Storage conditions
1 year at -70°C.
Usage disclaimer
For Research Only
Biological Information
Background
MAK, also called Male Germ Cell Associated Kinase, is a serine/threonine protein kinase and is involved in cell cycle regulation. It plays a role in the transcriptional coactivation of AR and may play a role in chromosomal stability in prostate cancer cells. [provided by RefSeq, Jan 2016]
Target class
Kinase
Family
CMGC
Accession Number
BC039825.1
Target Name
MAK
Target Alias
Male Germ Cell Associated Kinase; RP62; Serine/Threonine-Protein Kinase MAK; Testicular Secretory Protein Li 28
Origin
Human
Theoretical MW
Affinity Tag
GST
Product Specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
60% by SDS-PAGE and Coomassie blue staining.
Purification method
glutathione agarose; size exclusion chromatography
Sample Buffer
Specified activity
Refer to CoA
Application
Storage conditions
1 year at -70°C.
Usage disclaimer
For Research Only