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GRK6, active Human Recombinant Kinase Protein

N-terminal 6His-tagged recombinant, human full length GRK6 G protein coupled receptor kinase.

Biological information

Background
GRK6 is a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. Several transcript variants encoding different isoforms have been described for this gene. GenBank NM_001004106
Target class
Kinase
Family
AGC
Accession number
NM_001004105.1; NM_001004106.1; NM_002082.2
Target Name
GRK6, active Human Recombinant Kinase Protein
Target Alias
GRK6, FLJ32135, GPRK6
Origin
Human
Theori. MW
69.8 kDa
Affinity tag
6His

Product specifications

Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Refer to CoA for Purity
Purification method
Ni2+/NTA-agarose
Sample Buffer
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only

Chemical data

Background
GRK6 is a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. Several transcript variants encoding different isoforms have been described for this gene. GenBank NM_001004106
Compound name
Kinase
Catalog number
14-715
Molecular formula
CAS
MW
Ka
Percent composition

Product specifications

Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure

Kinase Activity Assay Biological information

Background
GRK6 is a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. Several transcript variants encoding different isoforms have been described for this gene. GenBank NM_001004106
Target class
Kinase
Family
AGC
Subfamily
Protein Name
GRK6
Protein Alias
GRK6, FLJ32135, GPRK6
Accession Number
NM_001004105.1; NM_001004106.1; NM_002082.2
UniProt Number
Gene Name
Gene ID
Gene Aliases
Target Species
Human

Kinase Activity Assay Usage

Product Type
Application
Storage Conditions
6 months at -70°C
Usage disclaimer

Kinase Activity Assay Information

Assay Type
Assay Measures

Biological Information

Background
GRK6 is a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. Several transcript variants encoding different isoforms have been described for this gene. GenBank NM_001004106
Target class
Kinase
Family
AGC
Accession Number
NM_001004105.1; NM_001004106.1; NM_002082.2
Target Name
GRK6
Target Alias
GRK6, FLJ32135, GPRK6
Origin
Human
Theoretical MW
Affinity Tag
6His

Product Specifications

Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Refer to CoA for Purity
Purification method
Ni2+/NTA-agarose
Sample Buffer
Specified activity
Refer to CoA
Application
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only

Biological Information

Background
GRK6 is a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. Several transcript variants encoding different isoforms have been described for this gene. GenBank NM_001004106
Target class
Kinase
Family
AGC
Accession Number
NM_001004105.1; NM_001004106.1; NM_002082.2
Target Name
GRK6
Target Alias
GRK6, FLJ32135, GPRK6
Origin
Human
Theoretical MW
Affinity Tag
6His

Product Specifications

Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Refer to CoA for Purity
Purification method
Ni2+/NTA-agarose
Sample Buffer
Specified activity
Refer to CoA
Application
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only
Datasheets
User Manual
File N°2
€ 389,00 EUR
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