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GRK5, active Human Recombinant Kinase Protein

N-terminal 6His-tagged recombinant, human full length GRK5.

Biological information

Background
GRK5 is a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs). GenBank NM_005308
Target class
Kinase
Family
AGC
Accession number
NM_005308.2
Target Name
GRK5, active Human Recombinant Kinase Protein
Target Alias
GRK5, GPRK5
Origin
Human
Theori. MW
71.6 kDa
Affinity tag
6His

Product specifications

Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Refer to CoA for Purity
Purification method
Ni2+/NTA-agarose
Sample Buffer
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only

Chemical data

Background
GRK5 is a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs). GenBank NM_005308
Compound name
Kinase
Catalog number
14-714
Molecular formula
CAS
MW
Ka
Percent composition

Product specifications

Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure

Kinase Activity Assay Biological information

Background
GRK5 is a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs). GenBank NM_005308
Target class
Kinase
Family
AGC
Subfamily
Protein Name
GRK5
Protein Alias
GRK5, GPRK5
Accession Number
NM_005308.2
UniProt Number
Gene Name
Gene ID
Gene Aliases
Target Species
Human

Kinase Activity Assay Usage

Product Type
Application
Storage Conditions
6 months at -70°C
Usage disclaimer

Kinase Activity Assay Information

Assay Type
Assay Measures

Biological Information

Background
GRK5 is a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs). GenBank NM_005308
Target class
Kinase
Family
AGC
Accession Number
NM_005308.2
Target Name
GRK5
Target Alias
GRK5, GPRK5
Origin
Human
Theoretical MW
Affinity Tag
6His

Product Specifications

Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Refer to CoA for Purity
Purification method
Ni2+/NTA-agarose
Sample Buffer
Specified activity
Refer to CoA
Application
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only

Biological Information

Background
GRK5 is a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs). GenBank NM_005308
Target class
Kinase
Family
AGC
Accession Number
NM_005308.2
Target Name
GRK5
Target Alias
GRK5, GPRK5
Origin
Human
Theoretical MW
Affinity Tag
6His

Product Specifications

Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Refer to CoA for Purity
Purification method
Ni2+/NTA-agarose
Sample Buffer
Specified activity
Refer to CoA
Application
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only
Datasheets
User Manual
File N°2
€ 389,00 EUR
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