CK1ε, active Human Recombinant Kinase Protein
10 µg of active CK1ε. N-terminal GST-tagged, recombinant, human CK1e amino acids 1-348.
Biological information
Background
CK1ε is a serine/threonine protein kinase and a member of the casein kinase I protein family, whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is found in the cytoplasm as a monomer and can phosphorylate a variety of proteins, including itself. This protein has been shown to phosphorylate period, a circadian rhythm protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Feb 2014]
Target class
Kinase
Family
Accession number
NM_001894.4
Target Name
CK1ε, active Human Recombinant Kinase Protein
Target Alias
Casein Kinase 1 EpsilonCasein Kinase I Isoform EpsilonCKIepsilonCasein Kinase 1Epsilon
Origin
Human
Theori. MW
67kDa
Affinity tag
GST
Product specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Purity 85% by SDS-PAGE and Coomassie blue staining.
Purification method
Purified using glutathione agarose followed by size exclusion chromatography.
Sample Buffer
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
1 year at -70°C.
Usage disclaimer
For Research Only
Chemical data
Background
CK1ε is a serine/threonine protein kinase and a member of the casein kinase I protein family, whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is found in the cytoplasm as a monomer and can phosphorylate a variety of proteins, including itself. This protein has been shown to phosphorylate period, a circadian rhythm protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Feb 2014]
Compound name
Kinase
Catalog number
16-045
Molecular formula
CAS
MW
Ka
Percent composition
Product specifications
Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure
Kinase Activity Assay Biological information
Background
CK1ε is a serine/threonine protein kinase and a member of the casein kinase I protein family, whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is found in the cytoplasm as a monomer and can phosphorylate a variety of proteins, including itself. This protein has been shown to phosphorylate period, a circadian rhythm protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Feb 2014]
Target class
Kinase
Family
Subfamily
Protein Name
CK1ε
Protein Alias
Casein Kinase 1 EpsilonCasein Kinase I Isoform EpsilonCKIepsilonCasein Kinase 1Epsilon
Accession Number
NM_001894.4
UniProt Number
Gene Name
Gene ID
Gene Aliases
Target Species
Human
Kinase Activity Assay Usage
Product Type
Application
Storage Conditions
1 year at -70°C.
Usage disclaimer
Kinase Activity Assay Information
Assay Type
Assay Measures
Biological Information
Background
CK1ε is a serine/threonine protein kinase and a member of the casein kinase I protein family, whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is found in the cytoplasm as a monomer and can phosphorylate a variety of proteins, including itself. This protein has been shown to phosphorylate period, a circadian rhythm protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Feb 2014]
Target class
Kinase
Family
Accession Number
NM_001894.4
Target Name
CK1ε
Target Alias
Casein Kinase 1 EpsilonCasein Kinase I Isoform EpsilonCKIepsilonCasein Kinase 1Epsilon
Origin
Human
Theoretical MW
Affinity Tag
GST
Product Specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Purity 85% by SDS-PAGE and Coomassie blue staining.
Purification method
Purified using glutathione agarose followed by size exclusion chromatography.
Sample Buffer
Specified activity
Refer to CoA
Application
Storage conditions
1 year at -70°C.
Usage disclaimer
For Research Only
Biological Information
Background
CK1ε is a serine/threonine protein kinase and a member of the casein kinase I protein family, whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is found in the cytoplasm as a monomer and can phosphorylate a variety of proteins, including itself. This protein has been shown to phosphorylate period, a circadian rhythm protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Feb 2014]
Target class
Kinase
Family
Accession Number
NM_001894.4
Target Name
CK1ε
Target Alias
Casein Kinase 1 EpsilonCasein Kinase I Isoform EpsilonCKIepsilonCasein Kinase 1Epsilon
Origin
Human
Theoretical MW
Affinity Tag
GST
Product Specifications
Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Purity 85% by SDS-PAGE and Coomassie blue staining.
Purification method
Purified using glutathione agarose followed by size exclusion chromatography.
Sample Buffer
Specified activity
Refer to CoA
Application
Storage conditions
1 year at -70°C.
Usage disclaimer
For Research Only