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CK1ε, active Human Recombinant Kinase Protein

10 µg of active CK1ε. N-terminal GST-tagged, recombinant, human CK1e amino acids 1-348.

Biological information

Background
CK1ε is a serine/threonine protein kinase and a member of the casein kinase I protein family, whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is found in the cytoplasm as a monomer and can phosphorylate a variety of proteins, including itself. This protein has been shown to phosphorylate period, a circadian rhythm protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Feb 2014]
Target class
Kinase
Family
Accession number
NM_001894.4
Target Name
CK1ε, active Human Recombinant Kinase Protein
Target Alias
Casein Kinase 1 EpsilonCasein Kinase I Isoform EpsilonCKIepsilonCasein Kinase 1Epsilon
Origin
Human
Theori. MW
67kDa
Affinity tag
GST

Product specifications

Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Purity 85% by SDS-PAGE and Coomassie blue staining.
Purification method
Purified using glutathione agarose followed by size exclusion chromatography.
Sample Buffer
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
1 year at -70°C.
Usage disclaimer
For Research Only

Chemical data

Background
CK1ε is a serine/threonine protein kinase and a member of the casein kinase I protein family, whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is found in the cytoplasm as a monomer and can phosphorylate a variety of proteins, including itself. This protein has been shown to phosphorylate period, a circadian rhythm protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Feb 2014]
Compound name
Kinase
Catalog number
16-045
Molecular formula
CAS
MW
Ka
Percent composition

Product specifications

Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure

Kinase Activity Assay Biological information

Background
CK1ε is a serine/threonine protein kinase and a member of the casein kinase I protein family, whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is found in the cytoplasm as a monomer and can phosphorylate a variety of proteins, including itself. This protein has been shown to phosphorylate period, a circadian rhythm protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Feb 2014]
Target class
Kinase
Family
Subfamily
Protein Name
CK1ε
Protein Alias
Casein Kinase 1 EpsilonCasein Kinase I Isoform EpsilonCKIepsilonCasein Kinase 1Epsilon
Accession Number
NM_001894.4
UniProt Number
Gene Name
Gene ID
Gene Aliases
Target Species
Human

Kinase Activity Assay Usage

Product Type
Application
Storage Conditions
1 year at -70°C.
Usage disclaimer

Kinase Activity Assay Information

Assay Type
Assay Measures

Biological Information

Background
CK1ε is a serine/threonine protein kinase and a member of the casein kinase I protein family, whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is found in the cytoplasm as a monomer and can phosphorylate a variety of proteins, including itself. This protein has been shown to phosphorylate period, a circadian rhythm protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Feb 2014]
Target class
Kinase
Family
Accession Number
NM_001894.4
Target Name
CK1ε
Target Alias
Casein Kinase 1 EpsilonCasein Kinase I Isoform EpsilonCKIepsilonCasein Kinase 1Epsilon
Origin
Human
Theoretical MW
Affinity Tag
GST

Product Specifications

Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Purity 85% by SDS-PAGE and Coomassie blue staining.
Purification method
Purified using glutathione agarose followed by size exclusion chromatography.
Sample Buffer
Specified activity
Refer to CoA
Application
Storage conditions
1 year at -70°C.
Usage disclaimer
For Research Only

Biological Information

Background
CK1ε is a serine/threonine protein kinase and a member of the casein kinase I protein family, whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is found in the cytoplasm as a monomer and can phosphorylate a variety of proteins, including itself. This protein has been shown to phosphorylate period, a circadian rhythm protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Feb 2014]
Target class
Kinase
Family
Accession Number
NM_001894.4
Target Name
CK1ε
Target Alias
Casein Kinase 1 EpsilonCasein Kinase I Isoform EpsilonCKIepsilonCasein Kinase 1Epsilon
Origin
Human
Theoretical MW
Affinity Tag
GST

Product Specifications

Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Purity 85% by SDS-PAGE and Coomassie blue staining.
Purification method
Purified using glutathione agarose followed by size exclusion chromatography.
Sample Buffer
Specified activity
Refer to CoA
Application
Storage conditions
1 year at -70°C.
Usage disclaimer
For Research Only
Datasheets
User Manual
File N°2
€ 689,00 EUR
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