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CDKL1, active Human Recombinant Kinase Protein

10 µg of active CDKL1. N-terminal 6His-tagged, recombinant, human CDKL1 amino acids 1-303.

Biological information

Background
CDKL1 is a member of a large family of CDC2-related serine/threonine protein kinases that accumulates primarily in the nucleus. Diseases associated with CDKL1 include Gene Duplication Disease. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is CDKL4. [provided by RefSeq, Nov 2018]
Target class
Kinase
Family
Ser/Thr Kinase
Accession number
NM_004196.3
Target Name
CDKL1, active Human Recombinant Kinase Protein
Target Alias
Cyclin Dependent Kinase Like 1KKIALRECyclin-Dependent Kinase-Like 1 (CDC2-Related Kinase)Protein Kinase P42 KKIALRESerine/Threonine Protein Kinase KKIALRE
Origin
Human
Theori. MW
39kDa
Affinity tag
6His

Product specifications

Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
83% by SDS-PAGE and Coomassie blue staining
Purification method
Purified using immobilized metal affinity chromatography.
Sample Buffer
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
1 year at -70°C.
Usage disclaimer
For Research Only

Chemical data

Background
CDKL1 is a member of a large family of CDC2-related serine/threonine protein kinases that accumulates primarily in the nucleus. Diseases associated with CDKL1 include Gene Duplication Disease. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is CDKL4. [provided by RefSeq, Nov 2018]
Compound name
Kinase
Catalog number
16-002
Molecular formula
CAS
MW
Ka
Percent composition

Product specifications

Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure

Kinase Activity Assay Biological information

Background
CDKL1 is a member of a large family of CDC2-related serine/threonine protein kinases that accumulates primarily in the nucleus. Diseases associated with CDKL1 include Gene Duplication Disease. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is CDKL4. [provided by RefSeq, Nov 2018]
Target class
Kinase
Family
Ser/Thr Kinase
Subfamily
Protein Name
CDKL1
Protein Alias
Cyclin Dependent Kinase Like 1KKIALRECyclin-Dependent Kinase-Like 1 (CDC2-Related Kinase)Protein Kinase P42 KKIALRESerine/Threonine Protein Kinase KKIALRE
Accession Number
NM_004196.3
UniProt Number
Gene Name
Gene ID
Gene Aliases
Target Species
Human

Kinase Activity Assay Usage

Product Type
Application
Storage Conditions
1 year at -70°C.
Usage disclaimer

Kinase Activity Assay Information

Assay Type
Assay Measures

Biological Information

Background
CDKL1 is a member of a large family of CDC2-related serine/threonine protein kinases that accumulates primarily in the nucleus. Diseases associated with CDKL1 include Gene Duplication Disease. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is CDKL4. [provided by RefSeq, Nov 2018]
Target class
Kinase
Family
Ser/Thr Kinase
Accession Number
NM_004196.3
Target Name
CDKL1
Target Alias
Cyclin Dependent Kinase Like 1KKIALRECyclin-Dependent Kinase-Like 1 (CDC2-Related Kinase)Protein Kinase P42 KKIALRESerine/Threonine Protein Kinase KKIALRE
Origin
Human
Theoretical MW
Affinity Tag
6His

Product Specifications

Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
83% by SDS-PAGE and Coomassie blue staining
Purification method
Purified using immobilized metal affinity chromatography.
Sample Buffer
Specified activity
Refer to CoA
Application
Storage conditions
1 year at -70°C.
Usage disclaimer
For Research Only

Biological Information

Background
CDKL1 is a member of a large family of CDC2-related serine/threonine protein kinases that accumulates primarily in the nucleus. Diseases associated with CDKL1 include Gene Duplication Disease. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is CDKL4. [provided by RefSeq, Nov 2018]
Target class
Kinase
Family
Ser/Thr Kinase
Accession Number
NM_004196.3
Target Name
CDKL1
Target Alias
Cyclin Dependent Kinase Like 1KKIALRECyclin-Dependent Kinase-Like 1 (CDC2-Related Kinase)Protein Kinase P42 KKIALRESerine/Threonine Protein Kinase KKIALRE
Origin
Human
Theoretical MW
Affinity Tag
6His

Product Specifications

Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
83% by SDS-PAGE and Coomassie blue staining
Purification method
Purified using immobilized metal affinity chromatography.
Sample Buffer
Specified activity
Refer to CoA
Application
Storage conditions
1 year at -70°C.
Usage disclaimer
For Research Only
Datasheets
User Manual
File N°2
€ 389,00 EUR
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