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CaM Kinase IIβ, active Human Recombinant Kinase Protein

N-terminal 6His-tagged recombinant CaM Kinase IIβ amino acids 1-315.

Biological information

Background
CAMK2B (Calcium/Calmodulin Dependent Protein Kinase II Beta) belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. GenBank AF081572
Target class
Kinase
Family
CAMK
Accession number
AF081572
Target Name
CaM Kinase IIβ, active Human Recombinant Kinase Protein
Target Alias
CAMK2B, CAMKB, CAM2, MGC29528, CAMK2
Origin
Human
Theori. MW
39.6 kDa
Affinity tag
6His

Product specifications

Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Refer to CoA for Purity
Purification method
Ni2+/NTA-agarose
Sample Buffer
Specified activity
Refer to CoA
Application
For Research Only
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only

Chemical data

Background
CAMK2B (Calcium/Calmodulin Dependent Protein Kinase II Beta) belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. GenBank AF081572
Compound name
Kinase
Catalog number
14-718
Molecular formula
CAS
MW
Ka
Percent composition

Product specifications

Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
For Research Only
Solubility structure

Kinase Activity Assay Biological information

Background
CAMK2B (Calcium/Calmodulin Dependent Protein Kinase II Beta) belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. GenBank AF081572
Target class
Kinase
Family
CAMK
Subfamily
Protein Name
CaMKIIb
Protein Alias
CAMK2B, CAMKB, CAM2, MGC29528, CAMK2
Accession Number
AF081572
UniProt Number
Gene Name
Gene ID
Gene Aliases
Target Species
Human

Kinase Activity Assay Usage

Product Type
Application
Storage Conditions
6 months at -70°C
Usage disclaimer

Kinase Activity Assay Information

Assay Type
Assay Measures

Biological Information

Background
CAMK2B (Calcium/Calmodulin Dependent Protein Kinase II Beta) belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. GenBank AF081572
Target class
Kinase
Family
CAMK
Accession Number
AF081572
Target Name
CaMKIIb
Target Alias
CAMK2B, CAMKB, CAM2, MGC29528, CAMK2
Origin
Human
Theoretical MW
Affinity Tag
6His

Product Specifications

Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Refer to CoA for Purity
Purification method
Ni2+/NTA-agarose
Sample Buffer
Specified activity
Refer to CoA
Application
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only

Biological Information

Background
CAMK2B (Calcium/Calmodulin Dependent Protein Kinase II Beta) belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. GenBank AF081572
Target class
Kinase
Family
CAMK
Accession Number
AF081572
Target Name
CaMKIIb
Target Alias
CAMK2B, CAMKB, CAM2, MGC29528, CAMK2
Origin
Human
Theoretical MW
Affinity Tag
6His

Product Specifications

Expression system
Expressed by baculovirus in Sf21 insect cells
Purity
Refer to CoA for Purity
Purification method
Ni2+/NTA-agarose
Sample Buffer
Specified activity
Refer to CoA
Application
Storage conditions
6 months at -70°C
Usage disclaimer
For Research Only
Datasheets
User Manual
File N°2
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