Txk Kinase Enzyme Activity Assay Kit
The Txk Kinase Enzyme Activity Assay Kit offers a validated, ready-to-use biochemical assay based on the renowned ADP Hunter™ Plus Assay platform from DiscoverX for accurately measuring kinase inhibitor efficacy. The kit includes recombinant Txk, substrate, ATP, detection reagents, and assay plates, enabling precise quantification of ADP accumulation. Designed to handle elevated ATP concentrations, this assay delivers robust, reliable data ideal for high-throughput screening (HTS) and other drug discovery applications.
Biological information
The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for Txk. It comes with all essential components, including recombinant Txk (Eurofins #14-761), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.
Txk is a non-receptor tyrosine kinase expressed predominantly in lymphoid cells that plays a redundant role with ITK in regulating the development, function and differentiation of T-cells. It is involved in signaling from many different receptors and participates in multiple downstream pathways, including regulation of the actin cytoskeleton. Txk has been implicated in immune-inflammatory diseases such as rheumatoid arthritis, bronchial asthma, and atopic dermatitis.
Product specifications
Chemical data
The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for Txk. It comes with all essential components, including recombinant Txk (Eurofins #14-761), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.
Txk is a non-receptor tyrosine kinase expressed predominantly in lymphoid cells that plays a redundant role with ITK in regulating the development, function and differentiation of T-cells. It is involved in signaling from many different receptors and participates in multiple downstream pathways, including regulation of the actin cytoskeleton. Txk has been implicated in immune-inflammatory diseases such as rheumatoid arthritis, bronchial asthma, and atopic dermatitis.
Product specifications
Kinase Activity Assay Biological information
The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for Txk. It comes with all essential components, including recombinant Txk (Eurofins #14-761), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.
Txk is a non-receptor tyrosine kinase expressed predominantly in lymphoid cells that plays a redundant role with ITK in regulating the development, function and differentiation of T-cells. It is involved in signaling from many different receptors and participates in multiple downstream pathways, including regulation of the actin cytoskeleton. Txk has been implicated in immune-inflammatory diseases such as rheumatoid arthritis, bronchial asthma, and atopic dermatitis.
RLK; TKL; BTKL; PTK4; PSCTK5
Kinase Activity Assay Usage
For Research Use Only
Kinase Activity Assay Information
Biological Information
The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for Txk. It comes with all essential components, including recombinant Txk (Eurofins #14-761), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.
Txk is a non-receptor tyrosine kinase expressed predominantly in lymphoid cells that plays a redundant role with ITK in regulating the development, function and differentiation of T-cells. It is involved in signaling from many different receptors and participates in multiple downstream pathways, including regulation of the actin cytoskeleton. Txk has been implicated in immune-inflammatory diseases such as rheumatoid arthritis, bronchial asthma, and atopic dermatitis.
Product Specifications
For Research Use Only
Biological Information
The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for Txk. It comes with all essential components, including recombinant Txk (Eurofins #14-761), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.
Txk is a non-receptor tyrosine kinase expressed predominantly in lymphoid cells that plays a redundant role with ITK in regulating the development, function and differentiation of T-cells. It is involved in signaling from many different receptors and participates in multiple downstream pathways, including regulation of the actin cytoskeleton. Txk has been implicated in immune-inflammatory diseases such as rheumatoid arthritis, bronchial asthma, and atopic dermatitis.
Product Specifications
For Research Use Only