SRMS Kinase Enzyme Activity Assay Kit
The SRMS Kinase Enzyme Activity Assay Kit offers a validated, ready-to-use biochemical assay based on the renowned ADP Hunter™ Plus Assay platform from DiscoverX for accurately measuring kinase inhibitor efficacy. The kit includes recombinant SRMS, substrate, ATP, detection reagents, and assay plates, enabling precise quantification of ADP accumulation. Designed to handle elevated ATP concentrations, this assay delivers robust, reliable data ideal for high-throughput screening (HTS) and other drug discovery applications.
Biological information
The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for SRMS. It comes with all essential components, including recombinant SRMS (Eurofins #16-036), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.
SRMS is a non-receptor tyrosine kinase in the SRC family of protein kinases. It contains SH3, SH2 and kinase catalytic domains but lacks some regulatory features found in classical SRC family kinases. Studies suggest a potential role for SRMS in autophagy and in regulating the activation of BRK/PTK6. Other cellular substrates that have been identified include DOK1, vimentin, Sam68, FBKP51, and OTUB1. Recent studies have also demonstrated the potential role of the kinase in various cancers, including gastric and colorectal cancers and platinum resistance in ovarian cancer.
Product specifications
Chemical data
The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for SRMS. It comes with all essential components, including recombinant SRMS (Eurofins #16-036), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.
SRMS is a non-receptor tyrosine kinase in the SRC family of protein kinases. It contains SH3, SH2 and kinase catalytic domains but lacks some regulatory features found in classical SRC family kinases. Studies suggest a potential role for SRMS in autophagy and in regulating the activation of BRK/PTK6. Other cellular substrates that have been identified include DOK1, vimentin, Sam68, FBKP51, and OTUB1. Recent studies have also demonstrated the potential role of the kinase in various cancers, including gastric and colorectal cancers and platinum resistance in ovarian cancer.
Product specifications
Kinase Activity Assay Biological information
The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for SRMS. It comes with all essential components, including recombinant SRMS (Eurofins #16-036), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.
SRMS is a non-receptor tyrosine kinase in the SRC family of protein kinases. It contains SH3, SH2 and kinase catalytic domains but lacks some regulatory features found in classical SRC family kinases. Studies suggest a potential role for SRMS in autophagy and in regulating the activation of BRK/PTK6. Other cellular substrates that have been identified include DOK1, vimentin, Sam68, FBKP51, and OTUB1. Recent studies have also demonstrated the potential role of the kinase in various cancers, including gastric and colorectal cancers and platinum resistance in ovarian cancer.
SRM; PTK70; C20orf148; dJ697K14.1
Kinase Activity Assay Usage
For Research Use Only
Kinase Activity Assay Information
Biological Information
The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for SRMS. It comes with all essential components, including recombinant SRMS (Eurofins #16-036), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.
SRMS is a non-receptor tyrosine kinase in the SRC family of protein kinases. It contains SH3, SH2 and kinase catalytic domains but lacks some regulatory features found in classical SRC family kinases. Studies suggest a potential role for SRMS in autophagy and in regulating the activation of BRK/PTK6. Other cellular substrates that have been identified include DOK1, vimentin, Sam68, FBKP51, and OTUB1. Recent studies have also demonstrated the potential role of the kinase in various cancers, including gastric and colorectal cancers and platinum resistance in ovarian cancer.
Product Specifications
For Research Use Only
Biological Information
The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for SRMS. It comes with all essential components, including recombinant SRMS (Eurofins #16-036), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.
SRMS is a non-receptor tyrosine kinase in the SRC family of protein kinases. It contains SH3, SH2 and kinase catalytic domains but lacks some regulatory features found in classical SRC family kinases. Studies suggest a potential role for SRMS in autophagy and in regulating the activation of BRK/PTK6. Other cellular substrates that have been identified include DOK1, vimentin, Sam68, FBKP51, and OTUB1. Recent studies have also demonstrated the potential role of the kinase in various cancers, including gastric and colorectal cancers and platinum resistance in ovarian cancer.
Product Specifications
For Research Use Only