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Rse Kinase Enzyme Activity Assay Kit

The Rse Kinase Enzyme Activity Assay Kit offers a validated, ready-to-use biochemical assay based on the renowned ADP Hunter™ Plus Assay platform from DiscoverX for accurately measuring kinase inhibitor efficacy. The kit includes recombinant Rse, substrate, ATP, detection reagents, and assay plates, enabling precise quantification of ADP accumulation. Designed to handle elevated ATP concentrations, this assay delivers robust, reliable data ideal for high-throughput screening (HTS) and other drug discovery applications.

Biological information

Background

The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for Rse. It comes with all essential components, including recombinant Rse (Eurofins #14-535), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.

Receptor tyrosine kinase Rse, also known as Tyro3, is part of the TAM receptor family alongside Axl and MerTK. It plays critical roles in cell survival, immune regulation, and nervous system function. Dysregulated Rse/Tyro3 signaling contributes to cancer progression, autoimmune diseases, and neurological disorders, highlighting its therapeutic potential. A Rse enzyme activity assay kit provides researchers with a powerful tool to study inhibitors, advancing the discovery of drugs targeting TAM receptor pathways.

Target class
Kinase
Family
AXL/UFO
Accession number
GenBank D17517.1
Target Name
Rse Kinase Enzyme Activity Assay Kit
Target Alias
TYRO3; BYK; DTK; SKY; TIF
Origin
Human
Theori. MW
Affinity tag

Product specifications

Expression system
Purity
Purification method
Sample Buffer
Specified activity
Application
Storage conditions
1 year at -70°C
Usage disclaimer

Chemical data

Background

The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for Rse. It comes with all essential components, including recombinant Rse (Eurofins #14-535), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.

Receptor tyrosine kinase Rse, also known as Tyro3, is part of the TAM receptor family alongside Axl and MerTK. It plays critical roles in cell survival, immune regulation, and nervous system function. Dysregulated Rse/Tyro3 signaling contributes to cancer progression, autoimmune diseases, and neurological disorders, highlighting its therapeutic potential. A Rse enzyme activity assay kit provides researchers with a powerful tool to study inhibitors, advancing the discovery of drugs targeting TAM receptor pathways.

Compound name
Kinase
Catalog number
44-535
Molecular formula
CAS
MW
Ka
Percent composition

Product specifications

Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
Solubility structure

Kinase Activity Assay Biological information

Background

The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for Rse. It comes with all essential components, including recombinant Rse (Eurofins #14-535), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.

Receptor tyrosine kinase Rse, also known as Tyro3, is part of the TAM receptor family alongside Axl and MerTK. It plays critical roles in cell survival, immune regulation, and nervous system function. Dysregulated Rse/Tyro3 signaling contributes to cancer progression, autoimmune diseases, and neurological disorders, highlighting its therapeutic potential. A Rse enzyme activity assay kit provides researchers with a powerful tool to study inhibitors, advancing the discovery of drugs targeting TAM receptor pathways.

Target class
Kinase
Family
AXL/UFO
Subfamily
Tyrosine kinase
Protein Name
Rse (TYRO3)
Protein Alias
TYRO3; BYK; DTK; SKY; TIF
Accession Number
GenBank D17517.1
UniProt Number
Q06418
Gene Name
TYRO3
Gene ID
7301
Gene Aliases

BYK; Dtk; RSE; Rek; Sky; Tif; Etk-2

Target Species
Human

Kinase Activity Assay Usage

Product Type
Enzyme Activity Assay Kits
Application
Drug Discovery & Development
Storage Conditions
1 year at -70°C
Usage disclaimer

For Research Use Only. These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.

Kinase Activity Assay Information

Assay Type
Enzymatic
Assay Measures
ADP Accumulation

Biological Information

Background

The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for Rse. It comes with all essential components, including recombinant Rse (Eurofins #14-535), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.

Receptor tyrosine kinase Rse, also known as Tyro3, is part of the TAM receptor family alongside Axl and MerTK. It plays critical roles in cell survival, immune regulation, and nervous system function. Dysregulated Rse/Tyro3 signaling contributes to cancer progression, autoimmune diseases, and neurological disorders, highlighting its therapeutic potential. A Rse enzyme activity assay kit provides researchers with a powerful tool to study inhibitors, advancing the discovery of drugs targeting TAM receptor pathways.

Target class
Kinase
Family
AXL/UFO
Accession Number
GenBank D17517.1
Target Name
Rse (TYRO3)
Target Alias
TYRO3; BYK; DTK; SKY; TIF
Origin
Human
Theoretical MW
Affinity Tag

Product Specifications

Expression system
Purity
Purification method
Sample Buffer
Enzymatic
Specified activity
Application
Drug Discovery & Development
Storage conditions
1 year at -70°C
Usage disclaimer

For Research Use Only. These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.

Biological Information

Background

The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for Rse. It comes with all essential components, including recombinant Rse (Eurofins #14-535), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.

Receptor tyrosine kinase Rse, also known as Tyro3, is part of the TAM receptor family alongside Axl and MerTK. It plays critical roles in cell survival, immune regulation, and nervous system function. Dysregulated Rse/Tyro3 signaling contributes to cancer progression, autoimmune diseases, and neurological disorders, highlighting its therapeutic potential. A Rse enzyme activity assay kit provides researchers with a powerful tool to study inhibitors, advancing the discovery of drugs targeting TAM receptor pathways.

Target class
Kinase
Family
AXL/UFO
Accession Number
GenBank D17517.1
Target Name
Rse (TYRO3)
Target Alias
TYRO3; BYK; DTK; SKY; TIF
Origin
Human
Theoretical MW
Affinity Tag

Product Specifications

Expression system
Purity
Purification method
Sample Buffer
Enzymatic
Specified activity
Application
Drug Discovery & Development
Storage conditions
1 year at -70°C
Usage disclaimer

For Research Use Only. These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.

Datasheets
44-535x Datasheet
User Manual
File N°2
Kinase Enzyme Activity Assay User Manual Rev 1
€ 950,00 EUR
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