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MAP3K19 Kinase Enzyme Activity Assay Kit

The MAP3K19 Kinase Enzyme Activity Assay Kit offers a validated, ready-to-use biochemical assay based on the renowned ADP Hunter™ Plus Assay platform from DiscoverX for accurately measuring kinase inhibitor efficacy. The kit includes recombinant MAP3K19, substrate, ATP, detection reagents, and assay plates, enabling precise quantification of ADP accumulation. Designed to handle elevated ATP concentrations, this assay delivers robust, reliable data ideal for high-throughput screening (HTS) and other drug discovery applications.

Biological information

Background

The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for MAP3K19. It comes with all essential components, including recombinant MAP3K19 (Eurofins #14-991), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.

Mitogen-activated protein kinase kinase kinase 19 (MAP3K19) is a serine/threonine kinase involved in MAPK signaling pathways. It regulates cell stress responses and inflammation, and has been linked to fibrotic diseases and cancer. A MAP3K19 enzyme activity assay kit provides researchers with a specialized tool to study kinase function and inhibitors, enabling the discovery of therapeutics targeting fibrotic and oncogenic pathways.

Target class
Kinase
Family
STE
Accession number
GenBank BC137277.1
Target Name
MAP3K19 Kinase Enzyme Activity Assay Kit
Target Alias
RCK, YSK4
Origin
Human
Theori. MW
Affinity tag

Product specifications

Expression system
Purity
Purification method
Sample Buffer
Specified activity
Application
Storage conditions
1 year at -70°C
Usage disclaimer

Chemical data

Background

The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for MAP3K19. It comes with all essential components, including recombinant MAP3K19 (Eurofins #14-991), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.

Mitogen-activated protein kinase kinase kinase 19 (MAP3K19) is a serine/threonine kinase involved in MAPK signaling pathways. It regulates cell stress responses and inflammation, and has been linked to fibrotic diseases and cancer. A MAP3K19 enzyme activity assay kit provides researchers with a specialized tool to study kinase function and inhibitors, enabling the discovery of therapeutics targeting fibrotic and oncogenic pathways.

Compound name
Kinase
Catalog number
44-991
Molecular formula
CAS
MW
Ka
Percent composition

Product specifications

Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
Solubility structure

Kinase Activity Assay Biological information

Background

The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for MAP3K19. It comes with all essential components, including recombinant MAP3K19 (Eurofins #14-991), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.

Mitogen-activated protein kinase kinase kinase 19 (MAP3K19) is a serine/threonine kinase involved in MAPK signaling pathways. It regulates cell stress responses and inflammation, and has been linked to fibrotic diseases and cancer. A MAP3K19 enzyme activity assay kit provides researchers with a specialized tool to study kinase function and inhibitors, enabling the discovery of therapeutics targeting fibrotic and oncogenic pathways.

Target class
Kinase
Family
STE
Subfamily
Serine/threonine kinase
Protein Name
MAP3K19
Protein Alias
RCK, YSK4
Accession Number
GenBank BC137277.1
UniProt Number
Q56UN5
Gene Name
MAP3K19
Gene ID
80122
Gene Aliases

RCK; YSK4

Target Species
Human

Kinase Activity Assay Usage

Product Type
Enzyme Activity Assay Kits
Application
Drug Discovery & Development
Storage Conditions
1 year at -70°C
Usage disclaimer

For Research Use Only. These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.

Kinase Activity Assay Information

Assay Type
Assay Measures
ADP Accumulation

Biological Information

Background

The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for MAP3K19. It comes with all essential components, including recombinant MAP3K19 (Eurofins #14-991), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.

Mitogen-activated protein kinase kinase kinase 19 (MAP3K19) is a serine/threonine kinase involved in MAPK signaling pathways. It regulates cell stress responses and inflammation, and has been linked to fibrotic diseases and cancer. A MAP3K19 enzyme activity assay kit provides researchers with a specialized tool to study kinase function and inhibitors, enabling the discovery of therapeutics targeting fibrotic and oncogenic pathways.

Target class
Kinase
Family
STE
Accession Number
GenBank BC137277.1
Target Name
MAP3K19
Target Alias
RCK, YSK4
Origin
Human
Theoretical MW
Affinity Tag

Product Specifications

Expression system
Purity
Purification method
Sample Buffer
Specified activity
Application
Drug Discovery & Development
Storage conditions
1 year at -70°C
Usage disclaimer

For Research Use Only. These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.

Biological Information

Background

The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for MAP3K19. It comes with all essential components, including recombinant MAP3K19 (Eurofins #14-991), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.

Mitogen-activated protein kinase kinase kinase 19 (MAP3K19) is a serine/threonine kinase involved in MAPK signaling pathways. It regulates cell stress responses and inflammation, and has been linked to fibrotic diseases and cancer. A MAP3K19 enzyme activity assay kit provides researchers with a specialized tool to study kinase function and inhibitors, enabling the discovery of therapeutics targeting fibrotic and oncogenic pathways.

Target class
Kinase
Family
STE
Accession Number
GenBank BC137277.1
Target Name
MAP3K19
Target Alias
RCK, YSK4
Origin
Human
Theoretical MW
Affinity Tag

Product Specifications

Expression system
Purity
Purification method
Sample Buffer
Specified activity
Application
Drug Discovery & Development
Storage conditions
1 year at -70°C
Usage disclaimer

For Research Use Only. These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.

Datasheets
44-991x Datesheet
User Manual
File N°2
Kinase Enzyme Activity Assay User Manual Rev 1
€ 950,00 EUR
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