JAK1 Kinase Enzyme Activity Assay Kit
The JAK1 Kinase Enzyme Activity Assay Kit offers a validated, ready-to-use biochemical assay based on the renowned ADP Hunter™ Plus Assay platform from DiscoverX for accurately measuring kinase inhibitor efficacy. The kit includes recombinant JAK1, substrate, ATP, detection reagents, and assay plates, enabling precise quantification of ADP accumulation. Designed to handle elevated ATP concentrations, this assay delivers robust, reliable data ideal for high-throughput screening (HTS) and other drug discovery applications.
Biological information
The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for JAK1. It comes with all essential components, including recombinant JAK1 (Eurofins #14-918), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.
Janus kinase 1 (JAK1) is a non-receptor tyrosine kinase that transmits signals from cytokine receptors to activate STAT transcription factors. JAK1 is essential for immune regulation and hematopoiesis. Dysregulated JAK1 signaling is implicated in autoimmune diseases, cancer, and inflammatory disorders. A JAK1 enzyme activity assay kit supports inhibitor characterization, advancing the development of targeted therapies including JAK inhibitors for immune-mediated diseases.
Product specifications
Chemical data
The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for JAK1. It comes with all essential components, including recombinant JAK1 (Eurofins #14-918), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.
Janus kinase 1 (JAK1) is a non-receptor tyrosine kinase that transmits signals from cytokine receptors to activate STAT transcription factors. JAK1 is essential for immune regulation and hematopoiesis. Dysregulated JAK1 signaling is implicated in autoimmune diseases, cancer, and inflammatory disorders. A JAK1 enzyme activity assay kit supports inhibitor characterization, advancing the development of targeted therapies including JAK inhibitors for immune-mediated diseases.
Product specifications
Kinase Activity Assay Biological information
The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for JAK1. It comes with all essential components, including recombinant JAK1 (Eurofins #14-918), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.
Janus kinase 1 (JAK1) is a non-receptor tyrosine kinase that transmits signals from cytokine receptors to activate STAT transcription factors. JAK1 is essential for immune regulation and hematopoiesis. Dysregulated JAK1 signaling is implicated in autoimmune diseases, cancer, and inflammatory disorders. A JAK1 enzyme activity assay kit supports inhibitor characterization, advancing the development of targeted therapies including JAK inhibitors for immune-mediated diseases.
JTK3; AIIDE; JAK1A; JAK1B
Kinase Activity Assay Usage
For Research Use Only. These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Kinase Activity Assay Information
Biological Information
The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for JAK1. It comes with all essential components, including recombinant JAK1 (Eurofins #14-918), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.
Janus kinase 1 (JAK1) is a non-receptor tyrosine kinase that transmits signals from cytokine receptors to activate STAT transcription factors. JAK1 is essential for immune regulation and hematopoiesis. Dysregulated JAK1 signaling is implicated in autoimmune diseases, cancer, and inflammatory disorders. A JAK1 enzyme activity assay kit supports inhibitor characterization, advancing the development of targeted therapies including JAK inhibitors for immune-mediated diseases.
Product Specifications
For Research Use Only. These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Biological Information
The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for JAK1. It comes with all essential components, including recombinant JAK1 (Eurofins #14-918), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.
Janus kinase 1 (JAK1) is a non-receptor tyrosine kinase that transmits signals from cytokine receptors to activate STAT transcription factors. JAK1 is essential for immune regulation and hematopoiesis. Dysregulated JAK1 signaling is implicated in autoimmune diseases, cancer, and inflammatory disorders. A JAK1 enzyme activity assay kit supports inhibitor characterization, advancing the development of targeted therapies including JAK inhibitors for immune-mediated diseases.
Product Specifications
For Research Use Only. These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.