IRAK4 Kinase Enzyme Activity Assay Kit
The IRAK4 Kinase Enzyme Activity Assay Kit offers a validated, ready-to-use biochemical assay based on the renowned ADP Hunter™ Plus Assay platform from DiscoverX for accurately measuring kinase inhibitor efficacy. The kit includes recombinant IRAK4, substrate, ATP, detection reagents, and assay plates, enabling precise quantification of ADP accumulation. Designed to handle elevated ATP concentrations, this assay delivers robust, reliable data ideal for high-throughput screening (HTS) and other drug discovery applications.
Biological information
The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for IRAK4. It comes with all essential components, including recombinant IRAK4 (Eurofins #14-599), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.
Interleukin-1 receptor-associated kinase 4 (IRAK4) is a critical mediator of the Toll-like receptor (TLR) and IL-1 receptor signaling pathways, driving innate immune responses. Genetic defects in IRAK4 result in primary immunodeficiencies, while excessive activation is associated with autoimmunity and inflammation. A IRAK4 enzyme activity assay kit provides researchers with a robust system for inhibitor testing, enabling the discovery of novel treatments for autoimmune and inflammatory diseases.
Product specifications
Chemical data
The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for IRAK4. It comes with all essential components, including recombinant IRAK4 (Eurofins #14-599), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.
Interleukin-1 receptor-associated kinase 4 (IRAK4) is a critical mediator of the Toll-like receptor (TLR) and IL-1 receptor signaling pathways, driving innate immune responses. Genetic defects in IRAK4 result in primary immunodeficiencies, while excessive activation is associated with autoimmunity and inflammation. A IRAK4 enzyme activity assay kit provides researchers with a robust system for inhibitor testing, enabling the discovery of novel treatments for autoimmune and inflammatory diseases.
Product specifications
Kinase Activity Assay Biological information
The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for IRAK4. It comes with all essential components, including recombinant IRAK4 (Eurofins #14-599), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.
Interleukin-1 receptor-associated kinase 4 (IRAK4) is a critical mediator of the Toll-like receptor (TLR) and IL-1 receptor signaling pathways, driving innate immune responses. Genetic defects in IRAK4 result in primary immunodeficiencies, while excessive activation is associated with autoimmunity and inflammation. A IRAK4 enzyme activity assay kit provides researchers with a robust system for inhibitor testing, enabling the discovery of novel treatments for autoimmune and inflammatory diseases.
IPD1; IMD67; REN64; IRAK-4; NY-REN-64
Kinase Activity Assay Usage
For Research Use Only. These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Kinase Activity Assay Information
Biological Information
The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for IRAK4. It comes with all essential components, including recombinant IRAK4 (Eurofins #14-599), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.
Interleukin-1 receptor-associated kinase 4 (IRAK4) is a critical mediator of the Toll-like receptor (TLR) and IL-1 receptor signaling pathways, driving innate immune responses. Genetic defects in IRAK4 result in primary immunodeficiencies, while excessive activation is associated with autoimmunity and inflammation. A IRAK4 enzyme activity assay kit provides researchers with a robust system for inhibitor testing, enabling the discovery of novel treatments for autoimmune and inflammatory diseases.
Product Specifications
For Research Use Only. These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Biological Information
The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for IRAK4. It comes with all essential components, including recombinant IRAK4 (Eurofins #14-599), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.
Interleukin-1 receptor-associated kinase 4 (IRAK4) is a critical mediator of the Toll-like receptor (TLR) and IL-1 receptor signaling pathways, driving innate immune responses. Genetic defects in IRAK4 result in primary immunodeficiencies, while excessive activation is associated with autoimmunity and inflammation. A IRAK4 enzyme activity assay kit provides researchers with a robust system for inhibitor testing, enabling the discovery of novel treatments for autoimmune and inflammatory diseases.
Product Specifications
For Research Use Only. These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.