ICK Kinase Enzyme Activity Assay Kit
The ICK Kinase Enzyme Activity Assay Kit offers a validated, ready-to-use biochemical assay based on the renowned ADP Hunter™ Plus Assay platform from DiscoverX for accurately measuring kinase inhibitor efficacy. The kit includes recombinant ICK, substrate, ATP, detection reagents, and assay plates, enabling precise quantification of ADP accumulation. Designed to handle elevated ATP concentrations, this assay delivers robust, reliable data ideal for high-throughput screening (HTS) and other drug discovery applications.
Biological information
The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for ICK. It comes with all essential components, including recombinant ICK (Eurofins #15-023), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.
ICK is a Ser/Thr protein kinase belonging to the CMGC family. It is required for ciliogenesis and is involved in the control of ciliary length. It may also play a key role in the development of multiple organ systems including cardiac development.
Overexpression of ICK in breast cancer has been shown to be required for tumor cell proliferation and chemoresistance. This oncogenic function is due to the phosphorylation of ERK1 by ICK. The kinase has also been shown to be responsible for the chemoresistance of small-cell lung cancer cells.
Product specifications
Chemical data
The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for ICK. It comes with all essential components, including recombinant ICK (Eurofins #15-023), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.
ICK is a Ser/Thr protein kinase belonging to the CMGC family. It is required for ciliogenesis and is involved in the control of ciliary length. It may also play a key role in the development of multiple organ systems including cardiac development.
Overexpression of ICK in breast cancer has been shown to be required for tumor cell proliferation and chemoresistance. This oncogenic function is due to the phosphorylation of ERK1 by ICK. The kinase has also been shown to be responsible for the chemoresistance of small-cell lung cancer cells.
Product specifications
Kinase Activity Assay Biological information
The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for ICK. It comes with all essential components, including recombinant ICK (Eurofins #15-023), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.
ICK is a Ser/Thr protein kinase belonging to the CMGC family. It is required for ciliogenesis and is involved in the control of ciliary length. It may also play a key role in the development of multiple organ systems including cardiac development.
Overexpression of ICK in breast cancer has been shown to be required for tumor cell proliferation and chemoresistance. This oncogenic function is due to the phosphorylation of ERK1 by ICK. The kinase has also been shown to be responsible for the chemoresistance of small-cell lung cancer cells.
ECO; ICK; MRK; CED6; LCK2; hICK; EJM10
Kinase Activity Assay Usage
For Research Use Only
Kinase Activity Assay Information
Biological Information
The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for ICK. It comes with all essential components, including recombinant ICK (Eurofins #15-023), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.
ICK is a Ser/Thr protein kinase belonging to the CMGC family. It is required for ciliogenesis and is involved in the control of ciliary length. It may also play a key role in the development of multiple organ systems including cardiac development.
Overexpression of ICK in breast cancer has been shown to be required for tumor cell proliferation and chemoresistance. This oncogenic function is due to the phosphorylation of ERK1 by ICK. The kinase has also been shown to be responsible for the chemoresistance of small-cell lung cancer cells.
Product Specifications
For Research Use Only
Biological Information
The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for ICK. It comes with all essential components, including recombinant ICK (Eurofins #15-023), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.
ICK is a Ser/Thr protein kinase belonging to the CMGC family. It is required for ciliogenesis and is involved in the control of ciliary length. It may also play a key role in the development of multiple organ systems including cardiac development.
Overexpression of ICK in breast cancer has been shown to be required for tumor cell proliferation and chemoresistance. This oncogenic function is due to the phosphorylation of ERK1 by ICK. The kinase has also been shown to be responsible for the chemoresistance of small-cell lung cancer cells.
Product Specifications
For Research Use Only