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Fyn Kinase Enzyme Activity Assay Kit

The Fyn Kinase Enzyme Activity Assay Kit offers a validated, ready-to-use biochemical assay based on the renowned ADP Hunter™ Plus Assay platform from DiscoverX for accurately measuring kinase inhibitor efficacy. The kit includes recombinant Fyn, substrate, ATP, detection reagents, and assay plates, enabling precise quantification of ADP accumulation. Designed to handle elevated ATP concentrations, this assay delivers robust, reliable data ideal for high-throughput screening (HTS) and other drug discovery applications.

Biological information

Background

The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for Fyn. It comes with all essential components, including recombinant Fyn (Eurofins #14-441), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.

Fyn tyrosine kinase (Fyn) is a member of the Src family kinases involved in T-cell receptor signaling, axon guidance, and cell adhesion. Also referred to as SLK or p59-Fyn, it plays roles in immune function, neuronal plasticity, and cancer development. Dysregulation of Fyn signaling has been associated with neurodegenerative disorders such as Alzheimer’s disease, immune dysfunction, and malignancies. A Fyn enzyme activity assay kit enables reliable testing of inhibitors and supports the development of novel therapeutics targeting Fyn pathways.

Target class
Kinase
Family
SRC
Accession number
GenBank M14333.1
Target Name
Fyn Kinase Enzyme Activity Assay Kit
Target Alias
Syn; c-syn; c-Fyn; SLK; p59-Fyn
Origin
Human
Theori. MW
Affinity tag

Product specifications

Expression system
Purity
Purification method
Sample Buffer
Specified activity
Application
Storage conditions
1 year at -70°C
Usage disclaimer

Chemical data

Background

The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for Fyn. It comes with all essential components, including recombinant Fyn (Eurofins #14-441), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.

Fyn tyrosine kinase (Fyn) is a member of the Src family kinases involved in T-cell receptor signaling, axon guidance, and cell adhesion. Also referred to as SLK or p59-Fyn, it plays roles in immune function, neuronal plasticity, and cancer development. Dysregulation of Fyn signaling has been associated with neurodegenerative disorders such as Alzheimer’s disease, immune dysfunction, and malignancies. A Fyn enzyme activity assay kit enables reliable testing of inhibitors and supports the development of novel therapeutics targeting Fyn pathways.

Compound name
Kinase
Catalog number
44-441
Molecular formula
CAS
MW
Ka
Percent composition

Product specifications

Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
Solubility structure

Kinase Activity Assay Biological information

Background

The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for Fyn. It comes with all essential components, including recombinant Fyn (Eurofins #14-441), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.

Fyn tyrosine kinase (Fyn) is a member of the Src family kinases involved in T-cell receptor signaling, axon guidance, and cell adhesion. Also referred to as SLK or p59-Fyn, it plays roles in immune function, neuronal plasticity, and cancer development. Dysregulation of Fyn signaling has been associated with neurodegenerative disorders such as Alzheimer’s disease, immune dysfunction, and malignancies. A Fyn enzyme activity assay kit enables reliable testing of inhibitors and supports the development of novel therapeutics targeting Fyn pathways.

Target class
Kinase
Family
SRC
Subfamily
Tyrosine kinase
Protein Name
Fyn
Protein Alias
Syn; c-syn; c-Fyn; SLK; p59-Fyn
Accession Number
GenBank M14333.1
UniProt Number
P06241
Gene Name
FYN
Gene ID
2534
Gene Aliases

SLK; SYN; p59-FYN

Target Species
Human

Kinase Activity Assay Usage

Product Type
Enzyme Activity Assay Kits
Application
Drug Discovery & Development
Storage Conditions
1 year at -70°C
Usage disclaimer

For Research Use Only. These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.

Kinase Activity Assay Information

Assay Type
Enzymatic
Assay Measures
ADP Accumulation

Biological Information

Background

The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for Fyn. It comes with all essential components, including recombinant Fyn (Eurofins #14-441), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.

Fyn tyrosine kinase (Fyn) is a member of the Src family kinases involved in T-cell receptor signaling, axon guidance, and cell adhesion. Also referred to as SLK or p59-Fyn, it plays roles in immune function, neuronal plasticity, and cancer development. Dysregulation of Fyn signaling has been associated with neurodegenerative disorders such as Alzheimer’s disease, immune dysfunction, and malignancies. A Fyn enzyme activity assay kit enables reliable testing of inhibitors and supports the development of novel therapeutics targeting Fyn pathways.

Target class
Kinase
Family
SRC
Accession Number
GenBank M14333.1
Target Name
Fyn
Target Alias
Syn; c-syn; c-Fyn; SLK; p59-Fyn
Origin
Human
Theoretical MW
Affinity Tag

Product Specifications

Expression system
Purity
Purification method
Sample Buffer
Enzymatic
Specified activity
Application
Drug Discovery & Development
Storage conditions
1 year at -70°C
Usage disclaimer

For Research Use Only. These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.

Biological Information

Background

The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for Fyn. It comes with all essential components, including recombinant Fyn (Eurofins #14-441), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.

Fyn tyrosine kinase (Fyn) is a member of the Src family kinases involved in T-cell receptor signaling, axon guidance, and cell adhesion. Also referred to as SLK or p59-Fyn, it plays roles in immune function, neuronal plasticity, and cancer development. Dysregulation of Fyn signaling has been associated with neurodegenerative disorders such as Alzheimer’s disease, immune dysfunction, and malignancies. A Fyn enzyme activity assay kit enables reliable testing of inhibitors and supports the development of novel therapeutics targeting Fyn pathways.

Target class
Kinase
Family
SRC
Accession Number
GenBank M14333.1
Target Name
Fyn
Target Alias
Syn; c-syn; c-Fyn; SLK; p59-Fyn
Origin
Human
Theoretical MW
Affinity Tag

Product Specifications

Expression system
Purity
Purification method
Sample Buffer
Enzymatic
Specified activity
Application
Drug Discovery & Development
Storage conditions
1 year at -70°C
Usage disclaimer

For Research Use Only. These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.

Datasheets
44-441 Datasheet
User Manual
File N°2
Kinase Enzyme Activity Assay User Manual Rev 1
€ 950,00 EUR
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