Brought to you by:

DYRK3 Kinase Enzyme Activity Assay Kit

The DYRK3 Kinase Enzyme Activity Assay Kit offers a validated, ready-to-use biochemical assay based on the renowned ADP Hunter™ Plus Assay platform from DiscoverX for accurately measuring kinase inhibitor efficacy. The kit includes recombinant DYRK3, substrate, ATP, detection reagents, and assay plates, enabling precise quantification of ADP accumulation. Designed to handle elevated ATP concentrations, this assay delivers robust, reliable data ideal for high-throughput screening (HTS) and other drug discovery applications.

Biological information

Background

The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for DYRK3. It comes with all essential components, including recombinant DYRK3 (Eurofins #15-002), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.

DYRK3 is a dual-specificity protein kinase belonging to the CMGC Ser/Thr protein kinase family.  The kinase promotes disassembly of several types of membraneless organelles during mitosis, such as stress granules, nuclear speckles and pericentriolar material. Its expression has been associated with a higher aggressiveness of glioblastoma cells and tumors.

Target class
Kinase
Family
CMGC
Accession number
NM_003582.2
Target Name
DYRK3 Kinase Enzyme Activity Assay Kit
Target Alias
REDK
Origin
Human
Theori. MW
Affinity tag

Product specifications

Expression system
Purity
Purification method
Sample Buffer
Specified activity
Application
Storage conditions
1 year at -70°C
Usage disclaimer

Chemical data

Background

The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for DYRK3. It comes with all essential components, including recombinant DYRK3 (Eurofins #15-002), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.

DYRK3 is a dual-specificity protein kinase belonging to the CMGC Ser/Thr protein kinase family.  The kinase promotes disassembly of several types of membraneless organelles during mitosis, such as stress granules, nuclear speckles and pericentriolar material. Its expression has been associated with a higher aggressiveness of glioblastoma cells and tumors.

Compound name
Kinase
Catalog number
45-002
Molecular formula
CAS
MW
Ka
Percent composition

Product specifications

Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
Solubility structure

Kinase Activity Assay Biological information

Background

The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for DYRK3. It comes with all essential components, including recombinant DYRK3 (Eurofins #15-002), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.

DYRK3 is a dual-specificity protein kinase belonging to the CMGC Ser/Thr protein kinase family.  The kinase promotes disassembly of several types of membraneless organelles during mitosis, such as stress granules, nuclear speckles and pericentriolar material. Its expression has been associated with a higher aggressiveness of glioblastoma cells and tumors.

Target class
Kinase
Family
CMGC
Subfamily
Serine/threonine/tyrosine kinase
Protein Name
DYRK3
Protein Alias
REDK
Accession Number
NM_003582.2
UniProt Number
O43781
Gene Name
DYRK3
Gene ID
8444
Gene Aliases

RED; REDK; DYRK5; hYAK3-2

Target Species
Human

Kinase Activity Assay Usage

Product Type
Enzyme Activity Assay Kits
Application
Drug Discovery & Development
Storage Conditions
1 year at -70°C
Usage disclaimer

For Research Use Only

Kinase Activity Assay Information

Assay Type
Enzymatic
Assay Measures
ADP Accumulation

Biological Information

Background

The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for DYRK3. It comes with all essential components, including recombinant DYRK3 (Eurofins #15-002), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.

DYRK3 is a dual-specificity protein kinase belonging to the CMGC Ser/Thr protein kinase family.  The kinase promotes disassembly of several types of membraneless organelles during mitosis, such as stress granules, nuclear speckles and pericentriolar material. Its expression has been associated with a higher aggressiveness of glioblastoma cells and tumors.

Target class
Kinase
Family
CMGC
Accession Number
NM_003582.2
Target Name
DYRK3
Target Alias
REDK
Origin
Human
Theoretical MW
Affinity Tag

Product Specifications

Expression system
Purity
Purification method
Sample Buffer
Enzymatic
Specified activity
Application
Drug Discovery & Development
Storage conditions
1 year at -70°C
Usage disclaimer

For Research Use Only

Biological Information

Background

The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for DYRK3. It comes with all essential components, including recombinant DYRK3 (Eurofins #15-002), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.

DYRK3 is a dual-specificity protein kinase belonging to the CMGC Ser/Thr protein kinase family.  The kinase promotes disassembly of several types of membraneless organelles during mitosis, such as stress granules, nuclear speckles and pericentriolar material. Its expression has been associated with a higher aggressiveness of glioblastoma cells and tumors.

Target class
Kinase
Family
CMGC
Accession Number
NM_003582.2
Target Name
DYRK3
Target Alias
REDK
Origin
Human
Theoretical MW
Affinity Tag

Product Specifications

Expression system
Purity
Purification method
Sample Buffer
Enzymatic
Specified activity
Application
Drug Discovery & Development
Storage conditions
1 year at -70°C
Usage disclaimer

For Research Use Only

Datasheets
45-002x Datasheet
User Manual
File N°2
Kinase Enzyme Activity Assay User Manual Rev 1
€ 950,00 EUR
SKU :
45-002
Purchase from our distributor
Button