CDKL5 Kinase Enzyme Activity Assay Kit
The CDKL5 Kinase Enzyme Activity Assay Kit offers a validated, ready-to-use biochemical assay based on the renowned ADP Hunter™ Plus Assay platform from DiscoverX for accurately measuring kinase inhibitor efficacy. The kit includes recombinant CDKL5, substrate, ATP, detection reagents, and assay plates, enabling precise quantification of ADP accumulation. Designed to handle elevated ATP concentrations, this assay delivers robust, reliable data ideal for high-throughput screening (HTS) and other drug discovery applications.
Biological information
The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for CDKL5. It comes with all essential components, including recombinant CDKL5 (Eurofins #14-998), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.
Cyclin-dependent kinase-like 5 (CDKL5) is a serine/threonine kinase expressed mainly in the brain, where it regulates neuronal signaling and synaptic development. Mutations in CDKL5 cause CDKL5 deficiency disorder, a severe form of epileptic encephalopathy. A CDKL5 enzyme activity assay kit provides researchers with a valuable system to study kinase activity and inhibitors, accelerating the search for treatments for rare neurological diseases.
Product specifications
Chemical data
The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for CDKL5. It comes with all essential components, including recombinant CDKL5 (Eurofins #14-998), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.
Cyclin-dependent kinase-like 5 (CDKL5) is a serine/threonine kinase expressed mainly in the brain, where it regulates neuronal signaling and synaptic development. Mutations in CDKL5 cause CDKL5 deficiency disorder, a severe form of epileptic encephalopathy. A CDKL5 enzyme activity assay kit provides researchers with a valuable system to study kinase activity and inhibitors, accelerating the search for treatments for rare neurological diseases.
Product specifications
Kinase Activity Assay Biological information
The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for CDKL5. It comes with all essential components, including recombinant CDKL5 (Eurofins #14-998), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.
Cyclin-dependent kinase-like 5 (CDKL5) is a serine/threonine kinase expressed mainly in the brain, where it regulates neuronal signaling and synaptic development. Mutations in CDKL5 cause CDKL5 deficiency disorder, a severe form of epileptic encephalopathy. A CDKL5 enzyme activity assay kit provides researchers with a valuable system to study kinase activity and inhibitors, accelerating the search for treatments for rare neurological diseases.
DEE2; ISSX; STK9; EIEE2; CFAP247
Kinase Activity Assay Usage
For Research Use Only. These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Kinase Activity Assay Information
Biological Information
The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for CDKL5. It comes with all essential components, including recombinant CDKL5 (Eurofins #14-998), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.
Cyclin-dependent kinase-like 5 (CDKL5) is a serine/threonine kinase expressed mainly in the brain, where it regulates neuronal signaling and synaptic development. Mutations in CDKL5 cause CDKL5 deficiency disorder, a severe form of epileptic encephalopathy. A CDKL5 enzyme activity assay kit provides researchers with a valuable system to study kinase activity and inhibitors, accelerating the search for treatments for rare neurological diseases.
Product Specifications
For Research Use Only. These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Biological Information
The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for CDKL5. It comes with all essential components, including recombinant CDKL5 (Eurofins #14-998), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.
Cyclin-dependent kinase-like 5 (CDKL5) is a serine/threonine kinase expressed mainly in the brain, where it regulates neuronal signaling and synaptic development. Mutations in CDKL5 cause CDKL5 deficiency disorder, a severe form of epileptic encephalopathy. A CDKL5 enzyme activity assay kit provides researchers with a valuable system to study kinase activity and inhibitors, accelerating the search for treatments for rare neurological diseases.
Product Specifications
For Research Use Only. These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.