Brought to you by:

CDK16/cyclin Y Kinase Enzyme Activity Assay Kit

The CDK16/cyclin Y Kinase Enzyme Activity Assay Kit offers a validated, ready-to-use biochemical assay based on the renowned ADP Hunter™ Plus Assay platform from DiscoverX for accurately measuring kinase inhibitor efficacy. The kit includes recombinant CDK16/cyclin Y, substrate, ATP, detection reagents, and assay plates, enabling precise quantification of ADP accumulation. Designed to handle elevated ATP concentrations, this assay delivers robust, reliable data ideal for high-throughput screening (HTS) and other drug discovery applications.

Biological information

Background

The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for CDK16/cyclin Y. It comes with all essential components, including recombinant CDK16/cyclin Y (Eurofins #16-041), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.

CDK16 is a cyclin-dependent kinase activated by binding to cyclin Y (CCNY) or its homologue cyclin Y-like 1 (CCNYL1) proteins. The kinase has been found to be involved in vesicle trafficking, neurite outgrowth, spermatogenesis, glucose transportation, skeletal myogenesis, and spindle orientation. It has also been shown to play key roles in cell growth and proliferation in multiple human cancers, such as prostate cancer, breast cancer, colorectal cancer and lung cancer.

Target class
Kinase
Family
CMGC
Accession number
NM_033018.1 (CDK16); BC094815.1 (cyclin Y)
Target Name
CDK16/cyclin Y Kinase Enzyme Activity Assay Kit
Target Alias
PCTAIRE-1; PCTAIRE1 (CDK16)
Origin
Human
Theori. MW
Affinity tag

Product specifications

Expression system
Purity
Purification method
Sample Buffer
Specified activity
Application
Storage conditions
1 year at -70°C
Usage disclaimer

Chemical data

Background

The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for CDK16/cyclin Y. It comes with all essential components, including recombinant CDK16/cyclin Y (Eurofins #16-041), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.

CDK16 is a cyclin-dependent kinase activated by binding to cyclin Y (CCNY) or its homologue cyclin Y-like 1 (CCNYL1) proteins. The kinase has been found to be involved in vesicle trafficking, neurite outgrowth, spermatogenesis, glucose transportation, skeletal myogenesis, and spindle orientation. It has also been shown to play key roles in cell growth and proliferation in multiple human cancers, such as prostate cancer, breast cancer, colorectal cancer and lung cancer.

Compound name
Kinase
Catalog number
46-041
Molecular formula
CAS
MW
Ka
Percent composition

Product specifications

Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
Solubility structure

Kinase Activity Assay Biological information

Background

The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for CDK16/cyclin Y. It comes with all essential components, including recombinant CDK16/cyclin Y (Eurofins #16-041), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.

CDK16 is a cyclin-dependent kinase activated by binding to cyclin Y (CCNY) or its homologue cyclin Y-like 1 (CCNYL1) proteins. The kinase has been found to be involved in vesicle trafficking, neurite outgrowth, spermatogenesis, glucose transportation, skeletal myogenesis, and spindle orientation. It has also been shown to play key roles in cell growth and proliferation in multiple human cancers, such as prostate cancer, breast cancer, colorectal cancer and lung cancer.

Target class
Kinase
Family
CMGC
Subfamily
Serine/threonine kinase
Protein Name
CDK16/cyclin Y
Protein Alias
PCTAIRE-1; PCTAIRE1 (CDK16)
Accession Number
NM_033018.1 (CDK16); BC094815.1 (cyclin Y)
UniProt Number
Q00536 (CDK16)
Gene Name
CDK16
Gene ID
5127 (CDK16)
Gene Aliases

PCTK1; PCTAIRE; PCTAIRE1; PCTGAIRE (CDK16)

Target Species
Human

Kinase Activity Assay Usage

Product Type
Enzyme Activity Assay Kits
Application
Drug Discovery & Development
Storage Conditions
1 year at -70°C
Usage disclaimer

For Research Use Only

Kinase Activity Assay Information

Assay Type
Enzymatic
Assay Measures
ADP Accumulation

Biological Information

Background

The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for CDK16/cyclin Y. It comes with all essential components, including recombinant CDK16/cyclin Y (Eurofins #16-041), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.

CDK16 is a cyclin-dependent kinase activated by binding to cyclin Y (CCNY) or its homologue cyclin Y-like 1 (CCNYL1) proteins. The kinase has been found to be involved in vesicle trafficking, neurite outgrowth, spermatogenesis, glucose transportation, skeletal myogenesis, and spindle orientation. It has also been shown to play key roles in cell growth and proliferation in multiple human cancers, such as prostate cancer, breast cancer, colorectal cancer and lung cancer.

Target class
Kinase
Family
CMGC
Accession Number
NM_033018.1 (CDK16); BC094815.1 (cyclin Y)
Target Name
CDK16/cyclin Y
Target Alias
PCTAIRE-1; PCTAIRE1 (CDK16)
Origin
Human
Theoretical MW
Affinity Tag

Product Specifications

Expression system
Purity
Purification method
Sample Buffer
Enzymatic
Specified activity
Application
Drug Discovery & Development
Storage conditions
1 year at -70°C
Usage disclaimer

For Research Use Only

Biological Information

Background

The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for CDK16/cyclin Y. It comes with all essential components, including recombinant CDK16/cyclin Y (Eurofins #16-041), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.

CDK16 is a cyclin-dependent kinase activated by binding to cyclin Y (CCNY) or its homologue cyclin Y-like 1 (CCNYL1) proteins. The kinase has been found to be involved in vesicle trafficking, neurite outgrowth, spermatogenesis, glucose transportation, skeletal myogenesis, and spindle orientation. It has also been shown to play key roles in cell growth and proliferation in multiple human cancers, such as prostate cancer, breast cancer, colorectal cancer and lung cancer.

Target class
Kinase
Family
CMGC
Accession Number
NM_033018.1 (CDK16); BC094815.1 (cyclin Y)
Target Name
CDK16/cyclin Y
Target Alias
PCTAIRE-1; PCTAIRE1 (CDK16)
Origin
Human
Theoretical MW
Affinity Tag

Product Specifications

Expression system
Purity
Purification method
Sample Buffer
Enzymatic
Specified activity
Application
Drug Discovery & Development
Storage conditions
1 year at -70°C
Usage disclaimer

For Research Use Only

Datasheets
46-041x Datasheet
User Manual
File N°2
Kinase Enzyme Activity Assay User Manual Rev 1
€ 950,00 EUR
SKU :
46-041
Purchase from our distributor
Button