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CDK15 Kinase Enzyme Activity Assay Kit

The CDK15 Kinase Enzyme Activity Assay Kit offers a validated, ready-to-use biochemical assay based on the renowned ADP Hunter™ Plus Assay platform from DiscoverX for accurately measuring kinase inhibitor efficacy. The kit includes recombinant CDK15, substrate, ATP, detection reagents, and assay plates, enabling precise quantification of ADP accumulation. Designed to handle elevated ATP concentrations, this assay delivers robust, reliable data ideal for high-throughput screening (HTS) and other drug discovery applications.

Biological information

Background

The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for CDK15/cyclin Y. It comes with all essential components, including recombinant CDK15/cyclin Y (Eurofins #14-996), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.

Cyclin-dependent kinase 15 (CDK15) is a less-characterized member of the CDK family that regulates cell cycle and transcriptional processes. Emerging evidence suggests CDK15 may play roles in cancer biology and cell survival pathways. A CDK15 enzyme activity assay kit provides a reliable tool for characterizing inhibitors, supporting the development of therapies targeting novel CDK family kinases.

Target class
Kinase
Family
CMGC
Accession number
GenBank NM_139158.1 (CDK15); GenBank BC094815.1 (cyclin Y)
Target Name
CDK15 Kinase Enzyme Activity Assay Kit
Target Alias
PFTAIRE-2; ALS2CR7
Origin
Human
Theori. MW
Affinity tag

Product specifications

Expression system
Purity
Purification method
Sample Buffer
Specified activity
Application
Storage conditions
1 year at -70°C
Usage disclaimer

Chemical data

Background

The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for CDK15/cyclin Y. It comes with all essential components, including recombinant CDK15/cyclin Y (Eurofins #14-996), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.

Cyclin-dependent kinase 15 (CDK15) is a less-characterized member of the CDK family that regulates cell cycle and transcriptional processes. Emerging evidence suggests CDK15 may play roles in cancer biology and cell survival pathways. A CDK15 enzyme activity assay kit provides a reliable tool for characterizing inhibitors, supporting the development of therapies targeting novel CDK family kinases.

Compound name
Kinase
Catalog number
44-996
Molecular formula
CAS
MW
Ka
Percent composition

Product specifications

Physical state
Purity (HPLC 214nm)
Retention time (RP18 HPLC)
CMC
Exact mass
Stability
Solubility structure

Kinase Activity Assay Biological information

Background

The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for CDK15/cyclin Y. It comes with all essential components, including recombinant CDK15/cyclin Y (Eurofins #14-996), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.

Cyclin-dependent kinase 15 (CDK15) is a less-characterized member of the CDK family that regulates cell cycle and transcriptional processes. Emerging evidence suggests CDK15 may play roles in cancer biology and cell survival pathways. A CDK15 enzyme activity assay kit provides a reliable tool for characterizing inhibitors, supporting the development of therapies targeting novel CDK family kinases.

Target class
Kinase
Family
CMGC
Subfamily
Serine/threonine kinase
Protein Name
CDK15
Protein Alias
PFTAIRE-2; ALS2CR7
Accession Number
GenBank NM_139158.1 (CDK15); GenBank BC094815.1 (cyclin Y)
UniProt Number
Q96Q40
Gene Name
CDK15
Gene ID
65061
Gene Aliases

PFTK2; ALS2CR7; PFTAIRE2

Target Species
Human

Kinase Activity Assay Usage

Product Type
Enzyme Activity Assay Kits
Application
Drug Discovery & Development
Storage Conditions
1 year at -70°C
Usage disclaimer

For Research Use Only. These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.

Kinase Activity Assay Information

Assay Type
Enzymatic
Assay Measures
ADP Accumulation

Biological Information

Background

The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for CDK15/cyclin Y. It comes with all essential components, including recombinant CDK15/cyclin Y (Eurofins #14-996), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.

Cyclin-dependent kinase 15 (CDK15) is a less-characterized member of the CDK family that regulates cell cycle and transcriptional processes. Emerging evidence suggests CDK15 may play roles in cancer biology and cell survival pathways. A CDK15 enzyme activity assay kit provides a reliable tool for characterizing inhibitors, supporting the development of therapies targeting novel CDK family kinases.

Target class
Kinase
Family
CMGC
Accession Number
GenBank NM_139158.1 (CDK15); GenBank BC094815.1 (cyclin Y)
Target Name
CDK15
Target Alias
PFTAIRE-2; ALS2CR7
Origin
Human
Theoretical MW
Affinity Tag

Product Specifications

Expression system
Purity
Purification method
Sample Buffer
Enzymatic
Specified activity
Application
Drug Discovery & Development
Storage conditions
1 year at -70°C
Usage disclaimer

For Research Use Only. These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.

Biological Information

Background

The Kinase Enzyme Activity Assay Kit provides a reliable biochemical method for evaluating kinase inhibitors. Built on HitHunter® assay technology, this kit is specifically optimized for CDK15/cyclin Y. It comes with all essential components, including recombinant CDK15/cyclin Y (Eurofins #14-996), a substrate, ATP, detection reagents, and assay plates. Each kit is accompanied by a Certificate of Analysis (COA), which outlines the recommended reaction conditions for accurate inhibitor detection. The supplied materials are sufficient to perform experiments covering two, six or twenty five 384-well assay plates.

Cyclin-dependent kinase 15 (CDK15) is a less-characterized member of the CDK family that regulates cell cycle and transcriptional processes. Emerging evidence suggests CDK15 may play roles in cancer biology and cell survival pathways. A CDK15 enzyme activity assay kit provides a reliable tool for characterizing inhibitors, supporting the development of therapies targeting novel CDK family kinases.

Target class
Kinase
Family
CMGC
Accession Number
GenBank NM_139158.1 (CDK15); GenBank BC094815.1 (cyclin Y)
Target Name
CDK15
Target Alias
PFTAIRE-2; ALS2CR7
Origin
Human
Theoretical MW
Affinity Tag

Product Specifications

Expression system
Purity
Purification method
Sample Buffer
Enzymatic
Specified activity
Application
Drug Discovery & Development
Storage conditions
1 year at -70°C
Usage disclaimer

For Research Use Only. These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.

Datasheets
44-996x Datasheet
User Manual
File N°2
Kinase Enzyme Activity Assay User Manual Rev 1
€ 1 300,00 EUR
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