Protransforming growth factor alpha

TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar.

PDB Code:
Native
Stable
Pure
Active protein
Recombinant protein
Human Origin
Entry name:
TGFA_HUMAN
Gene name:
TGFA
Uniprot accession:
P01135
Origin:
Homo sapiens (Human)
Protein family:
nd
Full-length:
160
Mass:
17006
Sequence:
MVPSAGQLALFALGIVLAACQALENSTSPLSADPPVAAAVVSHFNDCPDSHTQFCFHGTCRFLVQEDKPACVCHSGYVGARCEHADLLAVVAASQKKQAITALVVVSIVALAVLIITCVLIHCCQVRKHCEWCRALICRHEKPSALLKGRTACCHSETVV
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Expression systems: bacteria, yeast, insect cells, HEK & CHO mammalian cells
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