Leukocyte-specific transcript 1 protein

Possible role in modulating immune responses. Induces morphological changes including production of filopodia and microspikes when overexpressed in a variety of cell types and may be involved in dendritic cell maturation. Isoform 1 and isoform 2 have an inhibitory effect on lymphocyte proliferation.

PDB Code:
Native
Stable
Pure
Active protein
Recombinant protein
Human Origin
Entry name:
LST1_HUMAN
Gene name:
LST1
Uniprot accession:
O00453
Origin:
Homo sapiens (Human)
Protein family:
LST1
Full-length:
97
Mass:
10792
Sequence:
MLSRNDDICIYGGLGLGGLLLLAVVLLSACLCWLHRRVKRLERSWAQGSSEQELHYASLQRLPVPSSEGPDLRGRDKRGTKEDPRADYACIAENKPT
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Expression systems: bacteria, yeast, insect cells, HEK & CHO mammalian cells
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